[The hospital social service: a multi-year personal experience].

Among the categories of "health producers" in reference to the recently concluded hearing at the Ministry of health (8-10 July 2019) has space for the Hospital Social Service to which Social Workers are employed operating at public hospitals in Rome since 1970 when their function was mainly addressed to the individual hospitalized person establishing a "helping relationship" with the patient. From 1970 to today, there have been profound socio-cultural, legislative and regulatory changes that have induced Social Workers to adapt part of their functions to the "New" by facing a progressive growth of "social" problems forced to resolve during hospitalization. , thus highlighting a territorial shortage of care attributable also to the lack of information on the existential conditions of the residents of a specific Municipality.

The Caregiver Burden Inventory in evaluating the burden of caregivers of elderly demented patients: results from a multicenter study.

Background And Aims: The burden perceived by caregivers of patients with dementia is a fundamental prognostic aspect in the history of the disease. The aim of this study was to demonstrate the internal consistency of the Caregiver Burden Inventory (CBI), a scale used to quantify burdens in different aspects of a caregiver's life, and the influence of patients' and caregivers' characteristics on its different dimensions.

Methods: In this cross-sectional study, 419 demented patients and their caregivers were evaluated in 16 geriatric centers in Italy.

Plasma antioxidant status, immunoglobulin g oxidation and lipid peroxidation in demented patients: relevance to Alzheimer disease and vascular dementia.

A large body of evidence supports a role of oxidative stress in Alzheimer disease (AD) and in cerebrovascular disease. A vascular component might be critical in the pathophysiology of AD, but there is a substantial lack of data regarding the simultaneous behavior of peripheral antioxidants and biomarkers of oxidative stress in AD and vascular dementia (VaD). Sixty-three AD patients, 23 VaD patients and 55 controls were included in the study.

Lymphocyte oxidative DNA damage and plasma antioxidants in Alzheimer disease.

Context: A large body of experimental evidence suggests that in Alzheimer disease (AD) pathogenesis an important role is played by oxidative stress, but there is still a lack of data on in vivo markers of free radical-induced damage.

Objectives: To evaluate levels of 8-hydroxy-2'-deoxyguanosine (8-OHdG), a marker of oxidative damage to DNA, in peripheral lymphocytes; to measure plasma concentrations of several nonenzymatic antioxidants; and to assess the relationships between any observed changes in lymphocyte DNA 8-OHdG content and plasma antioxidant levels in patients with AD and healthy aged control subjects.

Subjects: Forty elderly outpatients with AD and 39 healthy age- and sex-matched controls were studied.