Publications by authors named "Paola Forte"

In this paper a mechanical characterization of low cost and simply available materials to build efficient anthropomorphic ultrasound elastography phantoms is described. The class of silicone materials was selected because of their deformability, durability and the possibility of reproducing specific tissue properties and shapes. Innovative formulations of silicone mixtures with echogenic and/or softening additives were tested.

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Among the available tools for the early diagnosis of breast cancer, the elastographic technique based on ultrasounds has many advantages such as the noninvasive measure, the absence of ionizing effects, the high tolerability by patients, and the wide diffusion of the ecographic machines. However this diagnostic procedure is strongly affected by many subjective factors and is considered not reliable enough even to reduce the number of biopsies used to identify the nature of lesions. Therefore in the literature experimental and numerical simulations on physical and virtual phantoms are presented to test and validate procedures and algorithms and to interpret elastosonographic results.

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Thirty-seven consecutive patients with acute decompensated heart failure (ADHF) admitted to emergency departments for acute dyspnea were investigated. Ten patients with acute exacerbation of chronic obstructive pulmonary disease and 10 patients with hypertension crisis were also included as controls. For each patient, a plasma amino-terminal pro-B-type natriuretic peptide (NTproBNP) concentration measurement was performed at admission, 4, 12, and 24 hours later, and on the day of discharge.

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Asthma is a chronic reversible respiratory disease characterized by inflammation and bronchial smooth muscle contraction. The therapeutic approach must improve the acute symptoms, avoid disease exacerbations and prevent the pulmonary functional decay.

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In this paper the Authors consider the concept of stunning/hibernating myocardium, analizing the most recent articles and reviews in literature, until April 2002 (database PubMed). Dysfunctional segments with normal perfusion and normal glucose utilization are considered to be "stunned", and dysfunctional segments with reduced perfusion and preserved glucose utilization are considered to be "hibernated". Together with the two major hypothesis (generation of oxygen-derived free radicals and transient calcium overload) in developing of dysfunctional myocardium after ischaemia, recent studies have demonstrated an important role in down-regulation of beta-adrenergic receptors both in the stunned and in the hibernated segments.

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