Publications by authors named "Panzetta M"
Article Synopsis
- Most patients with amyotrophic lateral sclerosis (ALS) currently lack effective pharmacological treatments due to the disease's complex nature and multiple underlying mechanisms.
- A review of 15 years of research by ALSUntangled highlighted 8 alternative and off-label treatments that have shown potential benefits in human trials, targeting various mechanisms like neuroinflammation and oxidative stress.
- The study suggests that combining these treatments, which address overlapping pathological mechanisms, could pave the way for more effective therapies for ALS in the future.
Article Synopsis
- The study analyzes the genus of mucophilic bacteria in the human gastrointestinal microbiota, finding that larger genomes may impact metabolic and immunological health.
- Through pangenomic analysis of 234 genomes and reanalysis of metagenomic datasets, the research identifies relationships between specific bacterial species and disease outcomes.
- Key findings highlight the need to differentiate subspecies and their varying correlations with conditions like obesity, inflammatory bowel disease, and cancer treatment outcomes, emphasizing their potential as probiotics.
are common members of the human gut microbiota. Multiple reports have emerged linking the abundance of to health benefits and disease risk in humans and animals. This review highlights findings linking species in the gastrointestinal (GI) tract to health outcomes across a spectrum of disorders, encompassing those that affect the digestive, respiratory, urinary, and central nervous systems.
View Article and Find Full Text PDFAmong the first microorganisms to colonize the human gut of breastfed infants are bacteria capable of fermenting human milk oligosaccharides (HMOs). One of the most abundant HMOs, 2'-fucosyllactose (2'-FL), may specifically drive bacterial colonization of the intestine. Recently, differential growth has been observed across multiple species of on various HMOs including 2'-FL.
View Article and Find Full Text PDFUnlabelled: Among the first microorganisms to colonize the human gut of breastfed infants are bacteria capable of fermenting human milk oligosaccharides (HMOs). One of the most abundant HMOs, 2'-fucosyllactose (2'-FL), may specifically drive bacterial colonization of the intestine. Recently, differential growth has been observed across multiple species of on various HMOs including 2'FL.
View Article and Find Full Text PDFis the most common sexually transmitted bacterial pathogen in humans and a frequent cause of asymptomatic, persistent infections leading to serious complications, particularly in young women. displays a unique obligate intracellular lifestyle involving the infectious elementary body and the replicative reticulate body. In the presence of stressors such as gamma-interferon (IFNγ) or beta-lactam antibiotics, undergoes an interruption in its replication cycle and enters a viable but non-cultivable state.
View Article and Find Full Text PDFThe comprise a group of highly adapted bacterial pathogens sharing a unique intracellular lifestyle. Three species are pathogenic to humans: , and . is the leading bacterial cause of sexually-transmitted infections and infectious blindness worldwide.
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