Use of large language models as artificial intelligence tools in academic research and publishing among global clinical researchers.

With breakthroughs in Natural Language Processing and Artificial Intelligence (AI), the usage of Large Language Models (LLMs) in academic research has increased tremendously. Models such as Generative Pre-trained Transformer (GPT) are used by researchers in literature review, abstract screening, and manuscript drafting. However, these models also present the attendant challenge of providing ethically questionable scientific information.

Mupirocin-Doped α-Cellulose Nanopaper for Wound Dressing: Development, In Vitro Characterization and Antimicrobial Studies.

This research aimed to develop a mupirocin-doped α-cellulose nanopaper (MDAC-NP) as a wound dressing to accelerate wound healing while limiting localized bacterial growth. The α-cellulose nanofibrils suspension was prepared by ultrasonication followed by microfluidization and subsequently doped with 0.05% w/v mupirocin to prepare nanopaper (MDAC-NP-A).

Research about eye health and eye health services in Pacific Island Countries and Territories: a scoping review.

Background: We aimed to summarise the extent and nature of published research about eye health and eye health services in Pacific Island Countries and Territories since 1980.

Methods: We searched Medline, EMBASE, Global Health and Cochrane Library to identify publications about eye health and eye health services in 22 Pacific Island Countries and Territories from 1 January 1980 to 26 January 2024. Study selection and data extraction were conducted by two reviewers independently.

Rethinking Fistula Preservation in Anorectal Malformation Surgery: A Histopathological Perspective.

Objective:  This study aims to assess the histopathological characteristics of the fistulous tissue in males with anorectal malformation (ARM) to determine its suitability for use in constructing a neoanus.

Methods:  This prospective observational study included male ARM patients with recto-urethral fistula. All other types were excluded.

Management of urinary incontinence in girls with congenital pouch colon.

Purpose: This study describes the management of urinary incontinence (UI) in eight girls with congenital pouch colon (CPC) associated with anorectal malformation (ARM).

Methods: From 2013 to 2015, six girls with CPC and UI underwent bladder neck reconstruction (BNR). Four girls had complete UI (CUI) and two girls partial UI (PUI).

Multi-step forecasting of dissolved oxygen in River Ganga based on CEEMDAN-AdaBoost-BiLSTM-LSTM model.

Accurate prediction of Dissolved Oxygen (DO) is an integral part of water resource management. This study proposes a novel approach combining Complete Ensemble Empirical Mode Decomposition with Adaptive Noise (CEEMDAN) with AdaBoost and deep learning for multi-step forecasting of DO. CEEMDAN generates Intrinsic Mode Functions (IMFs) with different frequencies, capturing non-linear and non-stationary characteristics of the data.

Quarter-Century PET/CT Transformation of Oncology: Lymphoma.

The clinical landscape of lymphomas has changed dramatically over the last 2 decades, including significant progress made in the understanding and utilization of imaging modalities and the available treatment options for both indolent and aggressive lymphomas. Since the introduction of hybrid PET/CT scanners in 2001, the indications of 18F-fluorodeoxyglucose (FDG) PET/CT in the management of lymphomas have grown rapidly. In today's clinical practice, FDG PET/CT is used in successful management of the vast majority patients with lymphomas.

Analysis of the Efficacy of Elastography in Comparison with Dynamic Renal Nuclear Scintigraphy in the Evaluation of Unilateral Pelvi-Ureteric Junction Obstruction.

Introduction: In hydronephrosis due to pelviureteric junction obstruction (PUJO), an obstruction to urine flow may lead to increased pelvic pressure, which may cause interstitial fibrosis and renal impairment. Recently, there have been reports on renal pelvic assessment using ultrasound elastography (USE). This study was conducted to see if USE can evaluate PUJO and if it can be correlated to the findings of the dynamic renal nuclear scan.

Retrieval of a retained umbilical vein catheter at 6 months.

Umbilical venous catheterisation is carried out for the care of neonates who have very low birth weight and are critically ill. It is uncommon for catheter fragments to become fractured and retained. Here, we describe a case of a retained fractured umbilical vein catheter in an infant.

Prevalence of Diabetes and Diabetic Retinopathy in Far-western Province of Nepal.

Background: Although diabetes is emerging as growing public health problem, there is limited population based data about the prevalence of the disease in Nepal.

Methods: This cross-sectional population-based survey, conducted in the Far-western province of Nepal from April 2020 to April 2021, used standardized RAAB + DR methodology. Diabetes was diagnosed on the basis of treatment history and random blood sugar test results of greater than 200 mg/dl.

Genetic Clarification of Strains Bred and Cultivated in Korea Using the ITS and IGS1 rDNA Region Sequences.

is one of the broadly cultivated edible mushrooms in Korea. Most of the Korean strains used for cultivation and breeding are known as . Recently, this species has been reported to belong to a species complex.

Effect of Savirin or Ticagrelor Treatment on the Expression of Commonly Used Reference Genes in .

Reference genes are frequently used for the normalization of quantitative reverse transcriptase PCR (qRTPCR) data in gene expression studies. is one of the most common causes of biofilm-related infections. Savirin and ticagrelor show in vitro as well as in vivo antibiofilm activity against .

Intralesional steroid in the era of propranolol for infantile hemangioma-Do we need it?

Introduction: Despite its effectivity, there are reports of poor response to propranolol in the treatment of infantile hemangioma (IH). The literature is limited to the type of IH that fails to respond to propranolol. This study was conducted to analyze which types of hemangiomas respond poorly to propranolol and the effects of intralesional triamcinolone (IL TMC) in them.

(L.f.) Willd.: A Review on Bioactive Compounds and Their Health Promoting Functionalities.

With the advent of pandemics and infectious diseases, numerous research activities on natural products have been carried out to combat them. Researchers are investigating natural products for the treatment and/or management of various infectious diseases and/or disorders. (L.

Mental health literacy questionnaire-short version for adults (MHLq-SVa): validation study in China, India, Indonesia, Portugal, Thailand, and the United States.

Background: Mental Health Literacy (MHL) has become a focus of research in recent decades, as a prerequisite for early identification and intervention for mental health problems. Although several instruments have been developed for assessing MHL, there is a need for brief and psychometrically sound measures to capture important aspects of MHL in large and diverse adult samples. The present study aimed to: (1) provide a revised and shorter version of a previously validated questionnaire for assessing MHL; and (2) examine the psychometric properties of the MHLq-SVa in student samples from six different countries (China, India, Indonesia, Portugal, Thailand, and United States).

Study the Possibility of Creating Mucosal Valve Mechanism at Ureteric Orifice without Obstructing the Urine Outflow but Preventing the Urine Backflow into the Ureters.

Objective: To study the possibility of creating mucosal valve mechanism at ureteric orifice without obstructing the urine outflow but preventing the urine backflow into the ureters.

Materials And Methods: Ethical waiver was obtained from the institutional ethical committee. Prospective experimental study was conducted on the post-mortem specimen of intact bladder with urethra and bilateral ureters retrieved from the already slaughtered lamb available in the meat market.

Effect of savirin in the prevention of biofilm-related prosthetic joint infection.

Most of the arthroplasty surgery failure due to prosthetic joint infections (PJI) is caused by biofilm-associated . In a recent experimental study, savirin has been used to prevent and treat skin infections in animal models. We explored the application of savirin in a PJI mouse model to determine its utility as an adjunct therapy to prevent PJI.

Evaluation of Resident Satisfaction Towards Cataract Surgery Training in Nepalese Ophthalmology Residency Programs.

Introduction: Although cataract surgery training is considered an integral part of all ophthalmology residency programs in Nepal, there is no literature about the training patterns and its effectiveness. The objective was to study the perspectives of young ophthalmologists towards the patterns and quality of cataract surgery training in their residency programs.

Materials And Methods: An anonymous web-based survey was conducted among MD Ophthalmology graduates completing their residency between January 2018 and December 2020 in Nepal.

Bilateral Cryptophthalmus: First Case Report from Nepal.

Introduction: Cryptophthalmus is characterized by a partial or complete casing of the eyeball by the skin. Cryptophthalmus alongside other systemic abnormalities is well-known as Fraser syndrome. It is an unusual genetic disorder with limited literature.

Structure-property investigations in urea tethered iodinated triphenylamines.

Herein, we report structural, computational, and conductivity studies on urea-directed self-assembled iodinated triphenylamine (TPA) derivatives. Despite numerous reports of conductive TPAs, the challenges of correlating their solid-state assembly with charge transport properties hinder the efficient design of new materials. In this work, we compare the assembled structures of a methylene urea bridged dimer of di-iodo TPA (1) and the corresponding methylene urea di-iodo TPA monomer (2) with a di-iodo mono aldehyde (3) control.