Generalized Cost-Effectiveness Analysis of Pharmaceutical Interventions for Primary Prevention of Cardiovascular Disease in Thailand.

Objectives: To assess the cost-effectiveness of blood pressure (BP)-lowering and cholesterol-lowering drugs for cardiovascular disease (CVD) prevention.

Methods: We constructed a Markov model in which the Thai population was classified by 10-year absolute CVD risk and modeled the use of BP- and cholesterol-lowering drugs, including a "polypill" (three BP-lowering drugs and a statin). We applied "do-nothing" as the comparator, a health sector perspective on lifetime cost-effectiveness, 3% discounting of costs and effects, and used probabilistic sensitivity analysis.

Joint prevalence and control of hypercholesterolemia and hypertension in Thailand: third national health examination survey.

The prevalence, diagnosis, treatment, and control of hypercholesterolemia and/or hypertension were estimated for Thailand using data from a recent, nationally representative health examination survey. Multivariate logistic regression was used to assess factors associated with diagnosis, treatment, and control. In all, 14% of men and 17% of women had hypercholesterolemia, 23% and 21% had hypertension, and 5% and 6%, respectively, had both.

Blood pressure, cholesterol and cardiovascular disease in Thailand.

Background: Although associations between risk factors such as hypertension and hypercholesterolaemia, and cardiovascular disease (CVD) are well-established it is not known to what extent these associations are similar in people from different ethnicities or regions. This study aims to measure the contributions of systolic blood pressure (SBP) and total cholesterol (TC) to ischaemic heart disease (IHD) and stroke in the Thai population.

Methods And Results: Data from a Thai cohort study were used for analyses.

Prevalence of chronic kidney disease in Thai adults: a national health survey.

Background: The prevalence of patients with end stage renal disease (ESRD) who need dialysis and/or transplantation has more than doubled in Thailand during the past two decades. It has been suggested that therapeutic strategies to reduce the risk of ESRD and other complications in CKD are now available, thus the early recognition and the institution of proven therapeutic strategies are important and beneficial. We, therefore, aimed to determine the prevalence of CKD in Thai adults from the National Health Examination Survey of 2004.

Prevalence and management of prehypertension and hypertension by geographic regions of Thailand: the Third National Health Examination Survey, 2004.

Objective: To determine the prevalence of prehypertension and hypertension, and management of hypertension, by geographic regions of Thailand.

Methods: Using a stratified, multistage sampling design, data from a nationally representative sample of 39 290 individuals aged > or = 15 years were collected by interview, physical examination and blood sample.

Results: The prevalence of hypertension and prehypertension weighted to the national 2004 population was 22.

Use of script concordance test to assess pharmaceutical diabetic care: a pilot study in Thailand.

The script concordance (SC) test is an assessment tool designed to probe whether knowledge of examinees is efficiently organized for clinical actions. The aim of this study was to develop an SC test, and determine whether it could be used to differentiate novices from expert pharmacists in their ability to carry out clinical actions in the area of diabetes mellitus. The SC test was developed and validated according to guidelines proposed previously.