The impact of sports event platforms on user experience an empirical analysis of tencent sports events.

This study focuses on two issues: first, what are the factors that bring different user experiences to viewers on sports event platforms, and second, how should operators of sports event platforms better optimize the user experience of sports event platforms according to the influencing factors of viewers' experiences. This paper takes the Tencent sports event platform as an example, and takes the technology acceptance model as the basis, introduces the user experience wheel model, and the relevant variables of the information construction theory to construct the user experience model of the sports event platform. conducted an online survey on the viewers of Tencent's sports platform, and the complete replies of 312 individuals were included in the analysis.

The Effects of Perceived Social Support on Postpartum Anxiety: A Moderated Mediation Model.

Purpose: Previous literature showed that perceived social support, self-esteem and optimism all played critical roles in the developing of postpartum anxiety. However, the mechanisms of influence were still unclear. This study aimed to explore the underlying mechanism of the relationship among perceived social support, self-esteem, optimism and postpartum anxiety.

Trajectories and Predictors of Symptoms of Depression in Chinese Women From Early Pregnancy to the Early Postpartum Period.

Objective: To explore the trajectories and predictors of symptoms of depression in Chinese women from early pregnancy to 3 months after birth.

Design: Prospective cohort study.

Setting: Several maternal and child health care institutions and obstetric departments of general hospitals in Beijing, Jiangsu, Hunan, Sichuan, Shandong, Guangdong, and Shanxi provinces in China.

Maternal obesity accelerated non-alcoholic fatty liver disease in offspring mice by reducing autophagy.

Non-alcoholic fatty liver disease (NAFLD) is a chronic liver disease characterized by an excessive accumulation of triacylglycerol in the liver. Autophagy is a lysosome-dependent degradation product recovery process, which widely occurs in eukaryotic cells, responsible for the vital maintenance of cellular energy balance. Previously published studies have demonstrated that autophagy is closely related to NAFLD occurrence and maternal obesity increases the susceptibility of offspring to non-alcoholic fatty liver disease, however, the underlying mechanism of this remains unclear.

Neuroprotective effect of ketamine against TNF-α-induced necroptosis in hippocampal neurons.

Tumour necrosis factor-α (TNF-α), a crucial cytokine, has various homeostatic and pathogenic bioactivities. The aim of this study was to assess the neuroprotective effect of ketamine against TNF-α-induced motor dysfunction and neuronal necroptosis in male C57BL/6J mice in vivo and HT-22 cell lines in vitro. The behavioural testing results of the present study indicate that ketamine ameliorated TNF-α-induced neurological dysfunction.

Enhancing β-Carotene Production in by Perturbing Central Carbon Metabolism and Improving the NADPH Supply.

Beta (β)-carotene (CH; a provitamin) is a particularly important carotenoid for human health. Many studies have focused on engineering as an efficient heterologous producer of β-carotene. Moreover, several strains with potential for use in the industrial production of this provitamin have already been constructed via different metabolic engineering strategies.

Combinatorial expression of different β-carotene hydroxylases and ketolases in Escherichia coli for increased astaxanthin production.

In natural produced bacteria, β-carotene hydroxylase (CrtZ) and β-carotene ketolase (CrtW) convert β-carotene into astaxanthin. To increase astaxanthin production in heterologous strain, simple and effective strategies based on the co-expression of CrtZ and CrtW were applied in E. coli.

Engineering genome-reduced Bacillus subtilis for acetoin production from xylose.

Objectives: To investigate the capacity of a genome-reduced Bacillus subtilis strain as chassis cell for acetoin production from xylose.

Results: To endow the genome-reduced Bacillus subtilis strain BSK814 with the ability to utilize xylose, we inserted a native xyl operon into its genome and deleted the araR gene. The resulting strain BSK814A2 produced 2.

Wide-field fluorescence tomography with composited epi-illumination of multi-frequency sinusoidal patterns.

We present a spatial-frequency domain (SFD) fluorescence tomography (FT) for acquiring three-dimensional fluorophore distribution in turbid media. The approach uses a composited epi-illumination of multi-frequency sinusoidal patterns on a sample of semi-infinite geometry and demodulates the measured data with a generalized phase shifting scheme to calculate the modulation transfer function (MTF) at each frequency. This method results in a significantly reduced number of the optical field measurements, as compared to those with separate illumination of single-frequency sinusoidal patterns, and, thereby, achieves a fast data acquisition that is desired for a dynamic imaging application.

Reference-free determination of tissue absorption coefficient by modulation transfer function characterization in spatial frequency domain.

Background: Spatial frequency domain (SFD) measurement allows rapid and non-contact wide-field imaging of the tissue optical properties, thus has become a potential tool for assessing physiological parameters and therapeutic responses during photodynamic therapy of skin diseases. The conventional SFD measurement requires a reference measurement within the same experimental scenario as that for a test one to calibrate mismatch between the real measurements and the model predictions. Due to the individual physical and geometrical differences among different tissues, organs and patients, an ideal reference measurement might be unavailable in clinical trials.

[Effect of various ambient temperatures on activities of mitochondrial complex II in patients of deficiency-cold syndrome and deficiency-heat syndrome].

Objective: To explore activity laws of mitochondrial complex II in patients of deficiency-cold syndrome (DCS) and deficiency-heat syndrome (DHS) under various ambient temperatures.

Methods: Subjects were recruited by questionnaire and expert diagnosis from grade 1 - 3 undergraduates at Henan College of Traditional Chinese Medicine in November 2012, and assigned to a normal control group, the DCS group, and the DHS group, 20 in each group. Their venous blood samples were collected at two different temperature conditions.

A quantum dot based electrochemiluminescent immunosensor for the detection of pg level phenylethanolamine A using gold nanoparticles as substrates and electron transfer accelerators.

This study reports the development of an electrochemiluminescent (ECL) immunosensor for ultrasensitive detection of phenylethanolamine A (PA) based on CdSe quantum dots (QDs) and gold nanoparticles (GNPs). The GNPs/ovalbumin-PA/anti-PA-QD immunosensor was fabricated layer by layer using GNPs as substrates and electron transport accelerators. The use of GNPs greatly enhanced the sensitivity for detecting PA due to the excellent electron transportation ability and the large surface area of GNP carriers allowing several binding events of ovalbumin-PA on each nanosphere.

Quantum dots based electrochemiluminescent immunosensor by coupling enzymatic amplification for ultrasensitive detection of clenbuterol.

An ultrasensitive electrochemiluminescence (ECL) immunosensor based on CdSe quantum dots (QDs) has been designed for the detection of clenbuterol. The immunosensor was fabricated by layer by layer and characterized with atomic force microscopic images (AFM) and electrochemical impedance spectra (EIS). In oxygen-saturated pH=9.

Preparation of water-soluble CdSe quantum dots and its application for nitrite detection in the anodic electrochemiluminescence.

Water-soluble CdSe quantum dots (QDs) have been prepared by using L-cysteine as the stabilizer in an aqueous phase under the optimized conditions. The characteristics and shapes of CdSe QDs have been proposed on the basis of UV-Vis and fluorescence spectra. A rapid analytical method for electrochemiluminescence (ECL) determination of nitrite has been developed on the basis of the quenching effect on anodic ECL emission of CdSe QDs under the optimum experimental conditions.