Study on the co-occurrence of multiple health service needs throughout the lifecourse of rural residents in China based on association rules.

Objective: To understand the multiple health service needs of rural residents in China and explore the co-occurrence patterns of these needs throughout the entire life course, providing a basis for the formulation and optimization of health service packaging policies.

Methods: This study utilized a stratified random sampling method, resulting in a final sample size of 15,125 individuals. The R statistical software was employed to apply the Apriori algorithm to mine the co-occurrence relationships among multiple health service needs across the life course and to explore the packaging model of these services.

The impact of internet medical service on rural gender inequality in health opportunity: a cross-sectional study.

Background: The increasing popularity of Internet medical service may have alleviated the gender inequality in health opportunity faced by rural women. However, research to ascertain the association between Internet medical service and gender inequality in health opportunity is scarce. This study explored the impact of Internet medical service on gender inequality in health opportunity among rural women and the underlying mechanisms involved.

Roles of hydrogen bonding interactions and hydrophobic effects on enhanced water structure in aqueous solutions of amphiphilic organic molecules.

Insights into the solute-induced water structural transformations are essential to understand the role of water in biological and chemical reaction processes. Herein, the structural changes in water induced by amphiphilic organic molecules were investigated using concentration-dependent derivative Raman spectroscopy (DRS) combined with two-dimensional Raman correlation spectroscopy (2D Raman-COS). We shall restrict our attention in this work to binary mixtures of water with dimethyl sulfoxide (DMSO), acetone, and isopropanol (IPA), all of which have similar chemical structures.

Exploring electronic energy level structure and excited electronic states of β-carotene using DFT.

Carotenoids are a class of natural pigments that play a fundamental role in photosynthesis and optoelectronics. However, the complexity of their energy level structure and electronic states has prevented a clear interpretation of their photophysics and photochemistry. The mediating nonradiative decay of the bright S state to the dark S state of carotenoids involves a population of bridging intermediate state.

Intermolecular energy transfer-enhanced super-broadband stimulated Raman scattering in cyclohexane-benzene mixtures.

Supercontinuum radiation has found numerous applications in diverse fields encompassing spectroscopy, pulse compression, and tunable laser sources. Anomalous enhanced stimulated Raman scattering (SRS) of cyclohexane-benzene mixtures was obtained in this study. SRS of the pure solvent, the multi-order Stokes of the strongest fundamental vibration modes, and energy transfer in intra-molecular modes were observed.

Hydrogen-Bond Dynamics and Water Structure in Aqueous Ethylene Glycol Solution via Two-Dimensional Raman Correlation Spectroscopy.

The hydrogen-bond (H-bond) dynamics and water structural transitions in aqueous ethylene glycol (EG) solution were investigated on the basis of concentration- and temperature-dependent two-dimensional Raman correlation spectroscopy (2D Raman-COS). At room temperature, EG-induced enhancement of the water structure when the EG/water molar ratio is less than 1:28 resulted from the hydrophobic effect around the methylene groups of EG. The decrease in the temperature caused an enhancement of the Raman peak at about 3200 cm, representing an increase in the orderliness of water molecules.

PAS Domain-Containing Chemoreceptors Influence the Signal Sensing and Intestinal Colonization of .

Bacterial chemotaxis is the phenomenon in which bacteria migrate toward a more favorable niche in response to chemical cues in the environment. The methyl-accepting chemotaxis proteins (MCPs) are the principal sensory receptors of the bacterial chemotaxis system. Aerotaxis is a special form of chemotaxis in which oxygen serves as the signaling molecule; the process is dependent on the aerotaxis receptors (Aer) containing the Per-Arnt-Sim (PAS) domain.

Precise Design of Alginate Hydrogels Crosslinked with Microgels for Diabetic Wound Healing.

Alginate hydrogel has received great attention in diabetic wound healing. However, the limited tunability of the ionic crosslinking method prevents the delicate management of physical properties in response to diverse wound conditions. We addressed this issue by using a microgel particle (fabricated by zinc ions and coordinated through the complex of carboxymethyl chitosan and aldehyde hyaluronic acid) as a novel crosslinker.

Whole Transcriptomic Analysis of Key Genes and Signaling Pathways in Endogenous ARDS.

Objective: To analyze the differentially expressed genes (DEGs) in rats with endogenous acute respiratory distress syndrome (ARDS) lung injury and explore the pathogenesis and early diagnostic molecular markers using whole transcriptomic data.

Methods: Twelve 8-week-old male Sprague Dawley rats were selected and randomly and equally divided into ARDS lung injury group and normal control group. RNA was extracted from the left lung tissues of both the groups and sequenced using the paired-end sequencing mode of the Illumina Hiseq sequencing platform.

Identification and validation of autophagy-related genes in exogenous sepsis-induced acute respiratory distress syndrome.

Objective: To analyze the differential expression of autophagy-related genes of sepsis-induced acute respiratory distress syndrome (ARDS) as potential markers for early diagnosis.

Methods: Male Sprague-Dawley rats (aged 8 weeks) were selected and randomly divided into sepsis-induced ARDS group (n = 6) and a normal control group (n = 6). Lung tissue samples were collected for high-throughput sequencing using Illumina HiSeq sequencing platform in the paired-end sequencing mode.

-Mediated In Vitro Inhibition of Plasmid Transfer Is Reversed by the Intestinal Environment.

Colistin is regarded as an antibiotic of last resort against multidrug-resistant Gram-negative bacteria, including and . Colistin resistance is acquired by microorganisms via chromosome-mediated mutations or plasmid-mediated mobile colistin resistance () gene, in which the transfer of is the predominant factor underlying the spread of colistin resistance. However, the factors that are responsible for the spread of the gene are still unclear.

Heparin Protects Severe Acute Pancreatitis by Inhibiting HMGB-1 Active Secretion from Macrophages.

Heparin has shown benefits in severe acute pancreatitis (SAP) therapy, but the underlying mechanisms were unknown. Extracellular high-mobility group protein-1 (HMGB-1) has been regarded as a central mediator contributing to inflammation exacerbation and disease aggravation. We hypothesized heparin attenuated the disease by targeting HMGB-1-related pathways.

A Severe Acute Pancreatitis Mouse Model Transited from Mild Symptoms Induced by a "Two-Hit" Strategy with L-Arginine.

To develop a severe acute pancreatitis (SAP) model transited from mild symptoms, we investigated a "two-hit" strategy with L-arginine in mice. The mice were intraperitoneally injected with ice-cold L-arginine (4 g/kg) twice at an interval of 1 h on the first day and subjected to the repeated operation 72 h afterwards. The results showed the "two-hit" strategy resulted in the destructive damage and extensive necrosis of acinar cells in the pancreas compared with the "one-hit" model.

Structure comparison and anti-coagulant effects of the glycosaminoglycans from porcine duodenum and jejunum.

To make full use of the porcine sources and develop better choice of novel GAGs as anti-coagulants, two fractions of GAGs from the porcine jejunum (A) and duodenum (C) have been separated & purified. The products were further sulfated to give B and D in order to test the influence of sulfate pattern on the bioactivity. The results showed that the relative molecular weight range of A was 3000-50,000 (Mw, g/mol), whereas C had an average molecular weight of 75,885 (Mw, g/mol).

Zinc ions coordinated carboxymethyl chitosan-hyaluronic acid microgel for pulmonary drug delivery.

Microgel affords a porous and swollen microstructure for the establishment of pulmonary delivery system with sustained released properties. Here, we report a microgel (with the diameter around 4 μm) prepared with a precipitation method, synthesized by coordinating Zn to the Schiff base cross-linked carboxymethyl chitosan and glycol split hyaluronate. The microgel has shown well swollen and pH sensitive behaviors, high safety and biocompatibility in vitro.

Intramolecular Vibration Energy-Transfer-Driven Cascaded Stimulated Raman Scattering and Four-Wave Mixing in Benzene Series.

Cascaded stimulated Raman scattering (SRS) of benzene, bromobenzene, chlorobenzene, ethylbenzene, and toluene was investigated by a pulsed Nd:YAG laser with 532 nm wavelength. The results showed that the third-order Stokes SRS of the ring skeleton vibration (CC at 3006 cm) accompanied by another higher-frequency Stokes SRS of the CH stretching vibration (at 3066 cm), which arose only when the third-order Stokes SRS of the ring skeleton was produced, can be attributed to the vibration energy transfer between vibration energy levels of CC and CH. The Stokes and anti-Stokes SRS rings, which originated from the intramolecular energy-transfer-enhanced four-wave mixing (FWM) processes, can be observed only in the forward direction along different angles apart from the pump beam direction.

First-order convergence of Milstein schemes for McKean-Vlasov equations and interacting particle systems.

In this paper, we derive fully implementable first-order time-stepping schemes for McKean-Vlasov stochastic differential equations, allowing for a drift term with super-linear growth in the state component. We propose Milstein schemes for a time-discretized interacting particle system associated with the McKean-Vlasov equation and prove strong convergence of order 1 and moment stability, taming the drift if only a one-sided Lipschitz condition holds. To derive our main results on strong convergence rates, we make use of calculus on the space of probability measures with finite second-order moments.

Correction: Effect of molybdenum carbide concentration on the Ni/ZrO catalysts for steam-CO bi-reforming of methane.

[This corrects the article DOI: 10.1039/C5RA22237K.].

Multi-functional ion-sensor based on a photochromic diarylethene with a 1H-imidazo [4,5-f][1,10] phenanthroline unit.

A new asymmetrical diarylethene containing a 1H-imidazo [4,5-f][1,10] phenanthroline unit was synthesized. The compound showed typical photochromism and functioned as a notable fluorescence switch upon alternating irradiation with ultraviolet (UV) and visible light. Its closed-ring isomer could be used as a selective 'naked-eye' colorimetric sensor for Cu(2+), accompanied by a notable color change from blue to colorless.

Wolbachia-induced cytoplasmic incompatibility is associated with decreased Hira expression in male Drosophila.

Background: Wolbachia are obligate endosymbiotic bacteria that infect numerous species of arthropods and nematodes. Wolbachia can induce several reproductive phenotypes in their insect hosts including feminization, male-killing, parthenogenesis and cytoplasmic incompatibility (CI). CI is the most common phenotype and occurs when Wolbachia-infected males mate with uninfected females resulting in no or very low numbers of viable offspring.