Cryptic invasions of Pseudopolydora (Annelida: Spionidae), with description of a new species from Queensland, Australia.

During surveys worldwide, we collected adult and larval specimens of Pseudopolydora Czerniavsky, 1881 similar to P. achaeta Radashevsky & Hsieh, 2000 and P. rosebelae Radashevsky & Migotto, 2009 far from their type localities in Taiwan and Brazil, respectively.

A twin of Polydora hoplura (Annelida: Spionidae) from the Arabian (Persian) Gulf, with review of primers used for barcoding of Spionidae.

The spionid polychaete Polydora hoplura Claparède, 1868 has been widely recorded boring in shells of abalone, oysters, clams, barnacle tests and sponges in temperate and subtropical waters. Molecular studies have suggested conspecificity of individuals collected worldwide but showed high genetic variability of the species with the highest diversity of haplotypes in the South African population. We have compared the morphology and genetic data of shell-boring worms from Kuwait, which were previously assigned to P.

Proteomic profiling improves prognostic risk stratification of the Sarculator nomogram in soft tissue sarcomas of the extremities and trunk wall.

Background: High-risk soft tissue sarcomas of the extremities and trunk wall (eSTS), as defined by the Sarculator nomogram, are more likely to benefit from (neo)adjuvant anthracycline-based therapy compared to low/intermediate-risk patients. The biology underpinning these differential treatment outcomes remain unknown.

Methods: We analysed proteomic profiles and clinical outcomes of 123 eSTS patients.

Clinical Implications and Molecular Features of Extracellular Matrix Networks in Soft Tissue Sarcomas.

Purpose: The landscape of extracellular matrix (ECM) alterations in soft tissue sarcomas (STS) remains poorly characterized. We aimed to investigate the tumor ECM and adhesion signaling networks present in STS and their clinical implications.

Experimental Design: Proteomic and clinical data from 321 patients across 11 histological subtypes were analyzed to define ECM and integrin adhesion networks.

[The main provisions of programs of medical and social rehabilitation of patients with occupational diseases of ent organs].

The article discusses the main, modern provisions of the programs of medical and social rehabilitation of patients with occupational diseases of the ENT organs. The criteria of the degree of loss of professional ability to work in hearing loss and malignant neoplasms of the upper respiratory tract are presented. Rehabilitation programs and forms are developed taking into account the needs of the victim in medical, social and vocational rehabilitation, taking into account the potential capabilities and abilities of the victim to carry out professional, domestic and social activities.

The proteomic landscape of soft tissue sarcomas.

Soft tissue sarcomas (STS) are rare and diverse mesenchymal cancers with limited treatment options. Here we undertake comprehensive proteomic profiling of tumour specimens from 321 STS patients representing 11 histological subtypes. Within leiomyosarcomas, we identify three proteomic subtypes with distinct myogenesis and immune features, anatomical site distribution and survival outcomes.

Searching for a Home Port in a Polyvectic World: Molecular Analysis and Global Biogeography of the Marine Worm (Annelida: Spionidae).

The spionid polychaete Claparède, 1868 is a shell borer widely occurring across the world and considered introduced in many areas. It was originally described in the Gulf of Naples, Italy. Adult diagnostic features are the palps with black bands, prostomium weakly incised anteriorly, caruncle extending to the end of chaetiger 3, short occipital antenna, and heavy sickle-shaped spines in the posterior notopodia.

[New criteria for professional selection and professional suitability by hearing to work in conditions of exposure to industrial hazards].

New regulations of professional selection and professional suitability for the state of auditory function for persons entering for the first time and already working under the influence of harmful and (or) hazardous production factors are discussed.

A review of the worldwide distribution of Marenzelleria viridis, with new records for M. viridis, M. neglecta and Marenzelleria sp. (Annelida: Spionidae).

Marenzelleria Mesnil, 1896 is a small group of spionid polychaetes comprising five valid species, all of which appear similar to each other. The identification of worms based on morphological features is often confusing, and thus molecular data have been suggested as providing crucial additional diagnostic characters. Here we summarize and map available records of M.

The Extracellular Matrix in Soft Tissue Sarcomas: Pathobiology and Cellular Signalling.

Soft tissue sarcomas are rare cancers of mesenchymal origin or differentiation comprising over 70 different histological subtypes. Due to their mesenchymal differentiation, sarcomas are thought to produce and deposit large quantities of extracellular matrix (ECM) components. Interactions between ECM ligands and their corresponding adhesion receptors such as the integrins and the discoidin domain receptors play key roles in driving many fundamental oncogenic processes including uncontrolled proliferation, cellular invasion and altered metabolism.

[STUDY OF THE POSITION TOWARDS HEALTH AND HEALTHY LIFESTYLE OF RAILWAY WORKERS].

Purpose: determination of the risk factors increasing the probability of development of non-communicable diseases at employees of the railway industry and also value of a condition of conditions for maintaining the healthy lifestyle by employees.

Materials And Methods: 13,595 people were interviewed (1.5% of the staff).

[Medicinal products in the treatment and prevention of occupational diseases of the upper respiratory tract].

Occupational diseases of the upper respiratory tract (URT) represent a significant section of occupational pathology of the respiratory system, since the mucous membrane of the nasal cavity and paranasal sinuses is the outpost that first comes into contact with inhaled agents (pollutants), including professional aerosols. The pathogenesis of occupational diseases of URT is based on long-term contact of pollutants with cells of the scintillating epithelium and violation of the function of the mucociliary system of URT. Occupational diseases of URT include: chronic catarrhal, subatrophic, atrophic, hypertrophic rhinitis, rhinopharyngolaryngitis; all forms of laryngitis, laryngotracheobronchitis, allergic diseases.

[Coverage of issues of professional malignant neoplasms of the respiratory tract in modern clinical guidelines of the Ministry of Health of Russia].

Objective: Analysis and comparison of clinical guidelines (CG) on malignant neoplasms of the respiratory system, placed in the CG rubricator of the Ministry of Health of Russia, for the information they contain on the role of factors and working conditions of the working environment in the etiology of respiratory diseases, including the upper respiratory tract, and comparison this information with published and regularly updated data from the International Agency for Research on Cancer (IARC).

Material And Methods: Clinical recommendations from the heading of the Ministry of Health of Russia "Cancer of the laryngopharynx", "Cancer of the nasopharynx", "Cancer of the oropharynx", "Cancer of the nasal cavity and paranasal sinuses", "Cancer of the larynx", "Cancer of the trachea", "Cancer of the lung", and IARC data according to the List of Classifications by cancer sites with sufficient or limited evidence in humans dated 11/29/2019.

Results: The low level of registration of occupational cancer of the upper respiratory tract in Russia is due to an inadequate system of criteria for detecting this form of occupational pathology, a long latency period of diseases, and insufficient assessment of the history of information on the potential role of occupational carcinogens.

[Upper respiratory tract infection with new COVID-19 coronavirus infection and aspects of occupational pathology examination].

The article discusses the issues of a new coronovirus infection CAVID-19, which suddenly appeared from the end of January 2020. in China and actively, widely spread around the world. The SARS-CoV virus is assigned to group II pathogenicity.

[Modern ideas about the professional suitability of employees of regulated professions with middle ear pathology and the possibility of their return to work (analytical review of the literature)].

Fitness for work in persons with middle ear disease who are exposed to harmful work environment and their possible return to work was analyzed. Fitness for work expertise procedure in the Russian Federation is disclosed in detail. A list of medical contraindications to work in harmful and/or dangerous work environment according to hearing condition is given.

Molecular analysis of Spiophanes bombyx complex (Annelida: Spionidae) with description of a new species.

Spiophanes bombyx (Claparède, 1870) from the Gulf of Naples, Tyrrhenian Sea, Italy, was the first described Spiophanes with fronto-lateral horns on the prostomium. It was also considered the only horned species occurring in European waters. Our sequence data of five gene fragments suggest the presence of two horned sibling Spiophanes species in northern Europe: S.

[Key points of 'Noise-induced hearing loss' clinical guidelines].

In this article we present the key points of 'Noise-induced hearing loss' clinical guidelines, which are included to the Clinical Guidelines Classifier of the Ministry of Health of Russia (2018). We give the definition of 'Noise-induced hearing loss', disclose the main causes and pathogenetic features of hearing impairment in employees who are affected by intensive noise at work. We state the main clinical and diagnostic criteria, treatment and rehabilitation principles; present the basics of primary and secondary prevention of hearing impairment in 'noise-hazardous' workers.

Fibroblastic Reticular Cells Control Conduit Matrix Deposition during Lymph Node Expansion.

Lymph nodes (LNs) act as filters, constantly sampling peripheral cues. This is facilitated by the conduit network, a tubular structure of aligned extracellular matrix (ECM) fibrils ensheathed by fibroblastic reticular cells (FRCs). LNs undergo rapid 3- to 5-fold expansion during adaptive immune responses, but these ECM-rich structures are not permanently damaged.

[Medical and social rehabilitation of hearing impairment from occupational noise].

The article presents the main provisions of medical and social rehabilitation of various hearing disorders caused by industrial noise. Two forms of hearing organ pathology in accordance with ICD-10 are distinguished: 'Adverse effects of industrial noise' - Z57.0 and 'hearing Loss caused by noise' - H83.

[The importance of the quantitative assessment of the hearing impairment in the subjects employed under conditions of enhanced noise].

The article describes the domestic modern diagnostic and expert approaches to the quantitative assessment of the hearing impairment in the subjects employed under conditions of enhanced occupational noise. It is concluded that the quantitative criteria for the determination of the severity of hearing loss in the workers of the 'noisy' professions adopted in this country are comparable with the respective international standards of and approaches to the medico-social examination practiced worldwide.

[The criteria for the relationship between hearing impairment and professional occupation and the criteria for professional suitability in terms of hearing among the aeronautical personnel engaged in civilian aviation].

This article describes the main clinical features associated with the development and manifestations of disturbed sound perception in the members of the aeronautical personnel engaged in the Russian civilian aviation. The main expert criteria for the relationship between the diseases of the organs of hearing (as exemplified by chronic sensorineural hearing impairment) and professional occupation have been developed based on the results of the clinical and diagnostic examination with the use of whispered and loud speech acumetry, tonal threshold audiometry, speech audiometry, impedancometry and evoked optoacoustic emission. Civilian aviation sectoral approaches to the evaluation of professional suitability in terms of hearing among the aeronautical personnel are considered in accordance with the criteria adopted by the International Civil Aviation Organization (ICAO), a specialized UN agency that sets the international standards for the civilian aviation and co-ordinates its development with the purpose of enhancing the safety and effectiveness of flights.

Crenomytilus grayanus 40kDa calponin-like protein: cDNA cloning, sequence analysis, tissue expression, and post-translational modifications.

Calponin-like protein (CaP-40), a third major protein after actin and tropomyosin, has recently been identified by us in the Ca-regulated thin filaments of mussel Crenomytilus grayanus. It contains calponin homology domain, five calponin family repeats and possesses similar biochemical properties as vertebrate smooth muscle calponin. In this paper, we report a full-length cDNA sequence of CaP-40, study its expression pattern on mRNA and protein levels, evaluate CaP-40 post-translational modifications and perform protein-protein interaction analysis.

Influence of occupational noise on hearing: systematic review of foreign literature.

The article is aimed to systematically review evidence-based data published in foreign literature on influence of level and characteristics of occupational noise on hearing loss. Search of the literature was based on key words "occupational noise exposure, permissible exposure limit, dose-response relationship, acceptable noise level, noise-induced hearing loss" The authors studied 349 publications, 7 out of which were included into the present systematic review. Findings are that developed countries demonstrate a tendency to decreased prevalence of hearing loss among workers exposed to noise.

[Contemporary methodic approach to evaluation of acoustic load on civil aircraft crew members.].

The article characterizes occupational factors including acoustic ones that influence work conditions of civil aircraft crew members, presents methodic basis to evaluate parameters of aviation noise inside cabin, with consideration of additional load from aviaheadsets. To specify scientifically based method for calculating acoustic load on civil aircraft crew members in cabins, the authors measured noise parameters inside cabins of aircrafts used at present in Russia, and noise-proof properties of domestic and foreign aviaheadsets. Normalized values suggested: equivalent level of A sound over a month (LA,,m), over a year (La); suggestions for reference values: equivalent level of A sound (Leg), over an arbitrary period of piloting length (L,r); coefficient of piloting load.

[The occupational risk of hearing impairment associated with cardiovascular pathologies in the subjects engaged in 'noisy' industries].

The objective of the present study was to analyze the structure of concomitant somatic pathology in the subjects experiencing the occupational hearing problems. The study demonstrated the increase in the frequency of concomitant chronic diseases and the prevalence of polynosological conditions with the increasing severity of hearing impairment. It was shown that cardiovascular pathologies tend to enhance the risk of hearing loss in the employees engaged in «noisy» occupations.