Publications by authors named "Panigrahi M"

Objective: To assess the effects of inferior vena cava and/or hepatic vein (IVC±HV) venoplasty on liver volumetry and function in individuals with Budd Chiari syndrome (BCS) who present with ascites and at least one patent hepatic vein.

Methods: A retrospective analysis was conducted on the clinical data of 17 patients with BCS (6 males and 11 females, average age of 42.3 ± 11.

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Budd-Chiari syndrome with obstruction in the inferior vena cava causes increased venous pressure in the azygous-hemiazygous system and paravertebral venous plexus, which is transmitted to the epidural venous plexus, devoid of the valves. It causes epidural venous plexus engorgement and venous congestion and may present rarely with low back pain or radiating pain. However, patients developing lower limb weakness as a complication of Budd-Chiari syndrome is an infrequent and severe presentation.

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Background And Objectives: For stroke survivors (SS) who undergo decompressive craniectomy (DC), quality of life is intertwined with the care they receive. Burden on caregiver becomes an important determinant of recovery of SS. In this study, we aimed to analyze the determinants of burden on caregivers of SS who undergo DC.

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  • Mastitis is a complex disease affecting milk production and reproduction in dairy animals, worsened by breeding practices, climate change, and hygiene issues.
  • AI and advanced genomic techniques, such as predictive genomics and CRISPR, have shown promise in identifying genetic traits related to mastitis susceptibility.
  • Integration of these technologies supports the development of better diagnostic, preventive, and treatment strategies, offering the potential to enhance dairy herd health and farm profitability.
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  • Differentiating liver tumors is crucial for appropriate treatment and prognosis, but non-invasive methods often struggle due to overlapping features in imaging.
  • This study evaluated CT perfusion parameters in 48 patients to help distinguish hepatocellular carcinoma (HCC) from other liver tumors, using statistical analysis to identify significant perfusion metrics.
  • Results indicated that blood volume (BV) was particularly effective in differentiating HCC from other tumors, achieving a sensitivity of 96.6% and specificity of 80% at a threshold of 8.3 ml/100 ml/min, alongside several other significant perfusion parameters.
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Left-sided portal hypertension (LPH) refers to increased splenic venous pressure caused by splenic vein stenosis or occlusion. Pancreatitis is the leading cause of LPH. Typically, LPH remains asymptomatic, but it can lead to life-threatening hemorrhage from ruptured fundal varices in about 10% of patients.

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  • Thoracic tracheal tumors are uncommon and can present challenges for surgery and anesthesia, making their management complex.
  • This study focuses on the percutaneous trans-tracheal endoscopic approach (PTTEA) as a minimally invasive alternative for patients with tracheal tumors when traditional methods fail.
  • Out of 16 patients treated from 2015 to 2022, most had successful outcomes with benign tumors, while malignant tumors required further treatment after initial procedures; PTTEA proved to offer advantages like better access and fewer complications.
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Background: We evaluated whether preoperative functional status influenced surgical outcomes for patients with intramedullary spinal cord tumors (IMSCT).

Methods: We analyzed whether lower preoperative McCormick scores impacted primary outcomes for 78 consecutive patients with IMSCT of World Health Organization (WHO) grades I and II undergoing tumor resection between 2010 and 2018.

Results: Patients averaged 33.

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  • * Findings show that while most respondents view H. pylori as a gastric pathogen, there is considerable variation in their diagnostic approaches; over half relied on endoscopic biopsies instead of non-invasive testing.
  • * The results highlight a significant gap in adherence to established guidelines for diagnosing and treating H. pylori infections, indicating a need for improved education and adherence among practitioners in India.
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  • - Livestock is crucial for human livelihoods, providing food security, economic stability, and cultural significance, with domestication dating back over 10,000 years which has led to significant genetic changes in various species.
  • - Recent genomic technologies, like next-generation sequencing and genome-wide association studies, have improved understanding of the domestication process and genetic diversity in livestock, revealing how natural selection, genetic drift, and gene flow influence these populations.
  • - The integration of machine learning with genomic data is offering new insights into the roles of genes in adaptation, suggesting ways to enhance livestock management and resilience to challenges like climate change.
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To understand if the risk of biliary complications is higher with living donor liver transplantation (LDLT) compared to deceased donor liver transplantation (DDLT), the present meta-analysis was conducted to analyze the differences between these two types of liver transplantations. Three databases were searched from inception to September 2023 for comparative studies reporting biliary complications with LDLT and DDLT. Odds ratios (OR) with 95% confidence intervals were calculated for all the dichotomous outcomes.

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Background: Tenosynovial giant cell tumor is a rare soft tissue tumor of the synovium of joint, bursae, or tendon sheath. It is divided into localized or diffuse types on the basis of the growth pattern. Localized tenosynovial giant cell tumors are usually benign and treated successfully by excision.

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  • * Different regions have varying causes of BCS; in the West, hepatic vein thrombosis is common, while in Asia, membranous and short occlusions are more prevalent, impacting treatment strategies.
  • * Interventional treatments like angioplasty and shunting can alleviate the condition more effectively than surgery, although complications may arise, and some patients may ultimately need a liver transplant if therapies fail.
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 Around 5% of patients with cirrhosis of the liver develop hepatic hydrothorax (HH). For patients with refractory HH (RHH), transjugular intrahepatic portosystemic shunt (TIPS) has been investigated in small studies. Hence, the present meta-analysis aimed to summarize the current data on the outcome of TIPS in patients with RHH.

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Identifying genomic regions under selection is essential for understanding the genetic mechanisms driving species evolution and adaptation. Traditional methods often fall short in detecting complex, spatially varying selection signals. Recent advances in deep learning, however, present promising new approaches for uncovering subtle selection signals that traditional methods might miss.

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Cattle breed identification is crucial for livestock research and sustainable food systems, and advances in genomics and artificial intelligence present new opportunities to address these challenges. This study investigates the identification of the Tharparkar cattle breed using genomics tools combined with machine learning (ML) techniques. By leveraging data from the Bovine SNP 50K chip, we developed a breed-specific panel of single nucleotide polymorphisms (SNPs) for Tharparkar cattle and integrated data from seven other Indian cattle populations to enhance panel robustness.

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  • Epithelioid trophoblastic tumors are rare cancers that typically affect the uterus and endocervix in women, emerging from specific trophoblasts, and are very uncommon in men, often found at metastatic sites.* -
  • Distinguishing these tumors from similar conditions, like placental site trophoblastic tumor and squamous cell carcinoma, is crucial, relying on unique morphological and immunohistochemical features.* -
  • This report discusses a rare case of a primary testicular epithelioid trophoblastic tumor in a young man, marking it as the third documented male case and the first case with this tumor as the main histological type in a testicular germ cell tumor.*
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Introduction: Leptospirosis and melioidosis are common in tropical and temperate climates and can be acquired by exposure to contaminated water and soil. However, concomitant leptospirosis and melioidosis infection is rarely described in the literature. We report a case of leptospirosis-melioidosis coinfection and systematically review the literature.

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Background: Endoscopic ultrasound guided fine-needle aspiration (EUS FNA) is the first-line modality to diagnose suspected solid pancreatic malignant lesions. Elastography-guided FNA has been shown to improve the diagnostic yield of EUS FNA but prospective studies are limited. The aim of the study was to compare diagnostic accuracy, sensitivity and specificity of conventional and elastography-guided EUS FNA in patients with suspected malignant pancreatic solid masses.

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Advanced Non-Small Cell Lung Carcinoma (NSCLC) patients with gene rearrangement have shown significant therapeutic responses to tyrosine kinase inhibitors approved by the US Food and Drug Administration, with approximately 40 fusion partners documented in the existing literature. Our report highlights a novel fusion partner of that has demonstrated a conclusive response to the current standard of treatment.

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