Publications by Panida L Webb

Publications by authors named "Panida L Webb"

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A novel function of the Fe65 neuronal adaptor in estrogen receptor action in breast cancer cells.

Yuefeng Sun Ravi Kasiappan Jinfu Tang Panida L Webb Waise Quarni

J Biol Chem

May 2014

Fe65 is a multidomain adaptor with established functions in neuronal cells and neurodegeneration diseases. It binds to the C terminus of the Aβ amyloid precursor protein and is involved in regulating gene transcription. The present studies show that Fe65 is expressed in breast cancer (BCa) cells and acts as an ERα transcriptional coregulator that is recruited by 17β-estradiol to the promoters of estrogen target genes.

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