Publications by authors named "Panickamparambil Gopalakrishnan Latha"
L. is a woody climber or liana distributed in south East Asia. It is a traditional medicinal plant with excellent curative effects against diarrhea, dysentery, and other stomach disorders.
View Article and Find Full Text PDFDeoxyelephantopin impairs growth of cervical carcinoma SiHa cells and induces apoptosis by targeting multiple molecular signaling pathways.
Arakkaveettil Kabeer Farha Sethumadhavannair Rajalekshmi Dhanya Sivasankaran Nair Mangalam Balakrishnan Sreedevi Geetha Panickamparambil Gopalakrishnan Latha
Cell Biol Toxicol
December 2014
Article Synopsis
- * The study identified that apoptosis was linked to the activation of various caspases and the production of reactive oxygen species, along with changes in key proteins related to cell survival and death.
- * Additionally, treatment with deoxyelephantopin resulted in G2/M phase cell cycle arrest, influenced by signaling pathways like STAT3/p53/p21 and MAPK, highlighting its complex role in cancer cell regulation.