Effect of electroacupuncture on inflammatory signal expression in local tissues of rats with chronic pelvic pain syndrome based on purinergic 2X7 receptor/NOD-like receptor pyrin domain-containing 3 signal pathway.

Objectives: To study the expression of inflammatory signal in local prostate tissue of chronic pelvic pain syndrome (CPPS) rats by electroacupuncture (EA) of Guanyuan (CV4), Zhongji (CV3), Huiyang (BL35) and Sanyinjiao (SP6), and to explore the possible mechanism of anti-inflammatory and analgesic effects of EA. METHODS：A total of 36 Sprague-Dawley male rats were randomly divided into three groups: control, model and EA (n=12 rats/group). The CPPS model was made by injection of CFA into ventral lobes of the prostate (0.

Integrated transcriptome and hormonal analysis of naphthalene acetic acid-induced adventitious root formation of tea cuttings (Camellia sinensis).

Background: Tea plant breeding or cultivation mainly involves propagation via cuttings, which not only ensures the inheritance of the excellent characteristics of the mother plant but also facilitates mechanized management. The formation of adventitious root (AR) determines the success of cutting-based propagation, and auxin is an essential factor involved in this process. To understand the molecular mechanism underlying AR formation in nodal tea cuttings, transcriptome and endogenous hormone analysis was performed on the stem bases of red (mature)- and green (immature)-stem cuttings of 'Echa 1 hao' tea plant as affected by a pulse treatment with naphthalene acetic acid (NAA).

Identifying key genes involved in yellow leaf variation in 'Menghai Huangye' based on biochemical and transcriptomic analysis.

Albino tea plants generally have higher theanine, which causes their tea leaves to taste fresher, and they are an important mutant for the breeding of tea plant varieties. Earlier, we reported an albino germplasm, 'Menghai Huangye' (MHHY), from Yunnan Province and found that it has a lower chlorophyll content during the yellowing stage, but the mechanism underlying low chlorophyll and the yellowing phenotype is still unclear. In this study, the pigment contents of MHHY_May (yellowing, low chlorophyll), MHHY_July (regreening, normal chlorophyll), and YK10_May (green leaves, normal chlorophyll) were determined, and the results showed that the lower chlorophyll content might be an important reason for the formation of the yellowing phenotype of MHHY.

Efficacy on rabbits with arrhythmia: needling acupoint of Neiguan (PC6) at shallow or deep depth, and retaining needles for 10, 20, or 30 min.

Objective: To compare the effects of Neiguan (PC6) acupuncture at different depths and retention time on arrhythmia duration, myocardial tissue morphology, mRNA expression level of L-type calcium channel α1C subunit and Ca2 + -Mg2 + -AtPase activity in tachirrhythmia model of rabbits.

Methods: The tachyarrhythmia model was made by intravenous injection of barium chloride into the ears of rabbits. A total of 56 healthy adult male New Zealand big-eared white rabbits, apply the random number table method, divided into normal control group (group A), model group (group B), shallow needling Neiguan (PC6) 10 min group (group C), shallow needling Neiguan (PC6) 20 min group (group D), shallow needling Neiguan (PC6) 30 min group (group E), deep needling Neiguan (PC6) 10 min group (group F), deep needling Neiguan (PC6) 20 min group (group G), deep needling Neiguan (PC6) 30 min group (group H), 7 animals in each group.

Menghai Huangye, a novel albino tea germplasm with high theanine content and a high catechin index.

Yunnan Province has a very wide diversity of tea germplasm resources. A variety of special tea germplasms with outstanding traits have been discovered, including tea germplasms with high anthocyanin content and low caffeine content. Albino tea cultivars generally have higher contents of theanine that contribute to the umami taste, and the quality of tea brewed from it is higher.

Expression Profile of Osteoclasts Following the Stimulation With Interleukin-23 in Mice.

Objectives: This study aims to analyze the expression profile of osteoclasts (OCs) following the stimulation with interleukin 23 (IL-23) in mice, which would imply the underlying effects of IL-23 on the function of OCs in inflammatory arthritis.

Materials And Methods: Mature OCs were induced from bone marrow mononuclear cells of 5 male mice (age 6 weeks; weighing 18-20 g) in the presence of macrophage-colony stimulating factor (50 ng/mL) and receptor activator of nuclear factor kappa B ligand (30 ng/mL) in vitro. The Agilent SurePrint G3 Mouse GE V2.

Comparative transcriptomic analysis of the tea plant (Camellia sinensis) reveals key genes involved in pistil deletion.

Background: The growth process of the tea plant (Camellia sinensis) includes vegetative growth and reproductive growth. The reproductive growth period is relatively long (approximately 1.5 years), during which a large number of nutrients are consumed, resulting in reduced tea yield and quality, accelerated aging, and shortened economic life of the tea plant.

Photocatalytic degradation of industrial acrylonitrile wastewater by F-S-Bi-TiO catalyst of ultrafine nanoparticles dispersed with SiO under natural sunlight.

Highly active photocatalyst, having certain anti-ionic interfering function, of F, S and Bi doped TiO/SiO was used for the first time to degrade the organic pollutants in acrylonitrile industrial wastewater under natural sunlight. The photocatalyst were prepared and characterized by UV-Vis, XRD, TEM, EDS, Nitrogen physical adsorption and XPS technique. UV-Vis analysis revealed addition of F, S and Bi into the lattice of TiO led to the expansion of TiO response in the visible region and hence the efficient separation of charge carrier.

Adsorption and photocatalytic degradation of benzene compounds on acidic F-TiO/SiO catalyst.

The adsorption and photocatalytic degradation performance of F-TiO/SiO catalyst towards a series of benzene compounds were studied. The results revealed that the F-TiO/SiO catalyst is superior to TiO P25 in adsorption capacity and photocatalytic degradation under simulant sunlight irradiation. The adsorptive capacity for chlorobenzene is the highest and the degradation rate is the greatest among these target pollutants.

Non-steroidal Anti-inflammatory Drugs Are Unlikely to Inhibit Radiographic Progression of Ankylosing Spondylitis: A Systematic Review.

To clarify if non-steroidal anti-inflammatory drugs (NSAIDs) could retard the disease progression of ankylosing spondylitis (AS). A systematic search of Embase, Pubmed, and the Cochrane Central Register of Controlled Trials (CCRCT) databases was conducted. Structural damage of AS was evaluated using spinal radiographs to assess modified Stoke Ankylosing Spondylitis Spine Score (mSASSS).

The Mutual Support Model of Mindfulness and Character Strengths.

Objectives: Numerous studies have confirmed robust relationships between general well-being and mindfulness or character strengths, respectively, but few have examined associations between mindfulness and character strengths. Two studies were carried out to explore these relationships comprehensively in the framework of the Values in Action (VIA) classification of character strengths.

Methods: In study 1, participants ( = 1335) completed validated assessments of mindfulness and character strengths, and the relationship between the two was investigated in a broad online sample.

Gallotannin 1,2,6-tri-O-galloyl-β-d-glucopyranose: Its availability and changing patterns in tea (Camellia sinensis).

Gallotannin 1,2,6-tri-O-galloyl-β-d-glucopyranose (1,2,6-TGGP) plays multiple roles against multidrug-resistant bacteria and other diseases. Nevertheless, its availability in tea (Camellia sinensis) has rarely been reported. Herein, the identification and verification of 1,2,6-TGGP from Camellia sinensis using ultra-performance liquid chromatography-quadrupole-time of flight mass spectrometry (UPLC-qTOF MS/MS), electrospray ionization mass spectrometry (ESI-MS) and nuclear magnetic resonance (NMR) were reported.

The language of character strengths: Predicting morally valued traits on social media.

Objective: Social media is increasingly being used to study psychological constructs. This study is the first to use Twitter language to investigate the 24 Values in Action Inventory of Character Strengths, which have been shown to predict important life domains such as well-being.

Method: We use both a top-down closed-vocabulary (Linguistic Inquiry and Word Count) and a data-driven open-vocabulary (Differential Language Analysis) approach to analyze 3,937,768 tweets from 4,423 participants (64.

Fusing character strengths and mindfulness interventions: Benefits for job satisfaction and performance.

In recent years, both mindfulness and character strengths have started to garner interest in industrial and organizational psychology. The growing research interest in their effects on employee well-being and performance, individually, has strong practical implications for organizations. Given the interconnection of mindfulness and character strengths, the present study examined the effectiveness of training that combined the two practices regarding well-being and work-related outcomes, and it tested the potential mediators of the effects at work.

Identification of key genes involved in catechin metabolism in tea seedlings based on transcriptomic and HPLC analysis.

Tea is a non-alcoholic beverage with many benefits to human health and thereby widely consumed in the world. It contains plenty of secondary metabolites and tea catechins are the characteristic compounds. To further elucidate the biosynthetic and regulatory mechanisms of catechins in tea, high performance liquid chromatography (HPLC) and transcriptome analysis were performed in tea seedlings of different growth stages.

Antityrosinase and antioxidant properties of mung bean seed proanthocyanidins: Novel insights into the inhibitory mechanism.

This study investigated the structure, antioxidant activity, antityrosinase activity and mechanism of proanthocyanidins from mung bean seed [Vigna radiata (L.) Wilczek]. The structural composition were characterized by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS), electrospray ionization-full-mass spectrometry (ESI-Full-MS), and high-pressure liquid chromatography-electrospray ionization-mass spectrometry (HPLC-ESI-MS) techniques.

An Initial Cross-Cultural Comparison of Adult Playfulness in Mainland China and German-Speaking Countries.

Compared with playfulness in infants and children, playfulness in adults is relatively under-studied. Although there is no empirical research comparing differences in adult playfulness across cultures, one might expect variations between Western and Eastern societies such as China. While playfulness is typically seen as a positive trait in Western culture, there are hints in Chinese culture that being playful has negative connotations (e.

Psychometric Comparisons of Benevolent and Corrective Humor across 22 Countries: The Virtue Gap in Humor Goes International.

Recently, two forms of virtue-related humor, benevolent and corrective, have been introduced. Benevolent humor treats human weaknesses and wrongdoings benevolently, while corrective humor aims at correcting and bettering them. Twelve marker items for benevolent and corrective humor (the BenCor) were developed, and it was demonstrated that they fill the gap between humor as temperament and virtue.

Different Modulatory Effects of IL-17, IL-22, and IL-23 on Osteoblast Differentiation.

Objectives: To examine the expressions of IL-17, IL-22, and IL-23 receptors in four osteoblast models and the effects of IL-17, IL-22, and IL-23 on osteoblasts.

Methods: Gene expression levels of receptors, alkaline phosphatase (ALP), osteocalcin (OCN), and Runt-related transcription factor 2 (Runx-2), were evaluated by RT-PCR and real-time RT-PCR. Proliferative responses and cell cycle analysis were detected by a CCK-8 assay and flow cytometry, respectively.

Photocatalytic decomposition of acrylonitrile with N-F codoped TiO2/SiO2 under simulant solar light irradiation.

The solid acid catalyst, N-F codoped TiO2/SiO2 composite oxide was prepared by a sol-gel method using NH4F as nitrogen and fluorine source. The prepared materials were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS), UV-Visible diffuse reflectance spectroscopy (UV-Vis), ammonia adsorption and temperature-programmed desorption (NH3-TPD), in situ Fourier transform infrared spectroscopy (FT-IR) and N2 physical adsorption isotherm. The photocatalytic activity of the catalyst for acrylonitrile degradation was investigated under simulant solar irradiation.

A new ligustrazine derivative--pharmacokinetic evaluation and antitumor activity by suppression of NF-kappaB/p65 and COX-2 expression in S180 mice.

A new anticancer ligustrazine derivative, 3beta-hydroxyolea-12-en-28-oic acid-3,5,6-trimethylpyrazin-2-methyl ester (T-OA, C38H58O3N2), was previously reported. It was synthesized via conjugating the effective antitumor ingredients of a classic traditional Chinese medicine (TCM) formulation. In the present study, anticancer efficacy of T-OA was evaluated in vivo using a murine sarcoma S180 model.