Publications by authors named "Pandolfi S"

Mandibular molar distalization is a complex orthodontic movement due to anatomic and biomechanical limitations. The opportunity to use a custom-made appliance with skeletal anchorage should be an advantageous alternative to traditional solutions: multiple extractions, interproximal reductions, vestibular inclination of incisal group. : A 14-year-old female patient with Class II malocclusion and ectopic upper and lower canines was treated in the lower arch with a custom-made appliance anchored on a mini-screw in the right buccal-shelf where the ectopy and crowding was severe.

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  • The study investigates the local structure and physical properties of molten silicates under extreme conditions, which are important for understanding planetary evolution.
  • Researchers used advanced techniques like in situ X-ray diffraction and high-power lasers to analyze shock-compressed liquid silicates with varying iron content at extremely high pressures.
  • Findings suggest that the densification of silicate networks continues beyond pressures found in Earth's interior, potentially affecting the formation and differentiation of rocky planets and super-Earths.
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  • Cardiovascular diseases (CVDs) are a serious global health issue, prompting extensive research focused on prevention through lifestyle changes, diet, and improved medical knowledge.
  • Ozone therapy is gaining attention as it stimulates the endothelial nitric oxide synthase/nitric oxide pathway, potentially offering new treatment options to mitigate endothelial and cardiac problems related to CVDs, such as atrial fibrillation.
  • This review aims to outline effective methods for using ozone in treating cardiovascular issues, particularly acute myocardial infarction from ischemic conditions, and emphasizes the need for further research in this area.
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Advances in cancer screening and treatment have improved survival after a diagnosis of cancer. As the number of cancer survivors as well as their overall life-expectancy increases, investigations of health-related quality of life (HRQOL) are critical in understanding the factors that promote the optimal experience over the course of survivorship. However, there is a dearth of information on determinants of HRQOL for African American cancer survivors as the vast majority of cohorts have been conducted predominantly among non-Hispanic Whites.

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Laser-driven dynamic compression experiments of plastic materials have found surprisingly fast formation of nanodiamonds (ND) via X-ray probing. This mechanism is relevant for planetary models, but could also open efficient synthesis routes for tailored NDs. We investigate the release mechanics of compressed NDs by molecular dynamics simulation of the isotropic expansion of finite size diamond from different P-T states.

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  • - Knee osteoarthritis (OA) is a chronic condition that causes pain, stiffness, and difficulty moving the knee joint, and current treatments like platelet-rich plasma and hyaluronic acid have shown limited effects on managing symptoms.
  • - A recent study explored the effectiveness of ozonated blood infusions for treating knee OA, finding that 250 patients showed approximately a 50% improvement in their health status after only five treatment sessions.
  • - The ozone therapy significantly reduced pain, disability, and stiffness, with positive outcomes reflected through WOMAC and Lequesne functional indexes for both men and women with varying severity of knee OA.
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Phonon scattering in metals is one of the most fundamental processes in materials science. However, understanding such processes has remained challenging and requires detailed information on interactions between phonons and electrons. We use an ultrafast electron diffuse scattering technique to resolve the nonequilibrium phonon dynamics in femtosecond-laser-excited tungsten in both time and momentum.

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  • * Two clinical studies demonstrated the effectiveness of ozone in treating infected post-surgical wounds and knee osteoarthritis, with notable reductions in infection and inflammation.
  • * The findings suggest that ozone therapy can enhance immune response, promote bacterial clearance, and alleviate symptoms in patients with specific conditions.
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Objective: In patients with breast cancer and positive hormone receptors, aromatase inhibitors are effective in reducing the risk of recurrences and are active in progressing the disease in this setting. On the other hand, fatigue and painful musculoskeletal side effects can significantly reduce treatment compliance. With no further treatment options to control these symptoms, non-pharmaceutical interventions, such as oxygen-ozone therapy, may play a role in managing rheumatologic symptomatology inasmuch.

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  • * It operates on the principle of hormesis at low doses, promoting cell protection through the activation of the body's antioxidant systems and having anti-inflammatory effects.
  • * As a bioregulator, ozone enhances mitochondrial function and influences complex regulatory mechanisms in cells, making it a novel approach in pharmacology and medical treatments.
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  • - Ozone, a form of oxygen, is being researched for its potential to help treat bacterial infections in wounds, especially those caused by drug-resistant bacteria.
  • - It works by activating a protein called Nrf2, which initiates a series of biological responses that enhance the function of immune cells known as macrophages in clearing infections.
  • - This review focuses on the latest findings regarding how ozone influences immune responses and its effectiveness against both regular and multidrug-resistant bacteria.
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A comment to: Ghaleh HEG, Izadi M, Javanbakht M, Ghanei M, Einollahi B, Jafari NJ, Alishiri G, Aslani J, Abolghasemi H, Simonetti V, Khafaei M, Zhao S, Saadat SH, Ahmadi M, Parvin S, Vazifedoust S, Alvanagh AG. Cytokine profile and antioxidants status in the moderate and severe COVID-19 patients: a trial of ozone therapy impact as a medicinal supplement. Inflammopharmacology.

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Purpose: As health care systems seek to screen for and address housing instability in patient populations, robust evidence linking unstable housing to patient-reported outcomes is needed. Housing instability may increase psychological distress in cancer survivors, potentially more so among African American cancer survivors who are also likely to experience disproportionate burden of housing instability. The purpose of this analysis was to estimate associations between housing instability and psychological distress in African Americans diagnosed with cancer.

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A prospecting campaign in the Maltese Islands has ensured the survival of several ancient olive trees ( L.), genetically distant from known cultivars. Most of these plants were abandoned or partially cultivated.

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Purpose: Pre-existing comorbidities play an important role in choice of cancer treatment. We retrospectively evaluated the relationship between pre-existing comorbidities and receipt of local and systemic therapy in a cohort of Black women with Stage I-III breast cancer.

Methods: The study population for analysis included 1169 women with Stage I-III disease enrolled in the Detroit Research on Cancer Survivors (ROCS) cohort.

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  • COVID-19 emerged in late 2019, with Italy being one of the first Western countries hit hard, facing a lack of knowledge and treatment guidelines initially.
  • The Italian Health Ministry suggested that treatment was only necessary if oxygen levels dropped below 92%, leading to delays in care that contributed to increased hospitalizations and a high death rate of 3.5%.
  • Volunteer groups swiftly began treating patients at home using non-steroidal anti-inflammatory drugs and repurposed medications, achieving better outcomes and fewer hospitalizations, highlighting the need for collaboration between healthcare institutions and community physicians for effective treatment strategies.
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We propose a hidden Markov model for multivariate continuous longitudinal responses with covariates that accounts for three different types of missing pattern: (I) partially missing outcomes at a given time occasion, (II) completely missing outcomes at a given time occasion (intermittent pattern), and (III) dropout before the end of the period of observation (monotone pattern). The missing-at-random (MAR) assumption is formulated to deal with the first two types of missingness, while to account for the informative dropout, we rely on an extra absorbing state. Estimation of the model parameters is based on the maximum likelihood method that is implemented by an expectation-maximization (EM) algorithm relying on suitable recursions.

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