Publications by authors named "Pandiaraj A"
The highly contagious malaria disease is spread by the female Anopheles mosquito. This disease results in a patient's death or incapacity to move their muscles, if it is not appropriately identified in the early stages. A Rapid Diagnostic Test (RDT) is a frequently used approach to find malaria cells in red blood cells.
View Article and Find Full Text PDFBackground: Plasmacytoid and myeloid dendritic cells play a vital role in the protection against viral infections. In COVID-19, there is an impairment of dendritic cell (DC) function and interferon secretion which has been correlated with disease severity.
Results: In this study, we described the frequency of DC subsets and the plasma levels of Type I (IFNα, IFNβ) and Type III Interferons (IFNλ1), IFNλ2) and IFNλ3) in seven groups of COVID-19 individuals, classified based on days since RT-PCR confirmation of SARS-CoV2 infection.
Article Synopsis
- T cells play a crucial role in protecting against SARS-CoV-2, but their specific types in recovering patients haven't been well-researched.
- The study measured T cell counts and types in COVID-19 patients at different recovery stages, finding an increase in memory T cells and a decrease in naïve and regulatory T cells over time.
- Severe COVID-19 cases showed lower lymphocyte counts and different levels of T cell subtypes and specific cytokines, highlighting significant changes in immune response during and after recovery.