Identifying sources of infiltration and inflow in sanitary sewers in a northern community: comparative assessment of selected methods.

Infiltration and inflow (I/I) into sanitary sewers causes numerous negative effects on the whole wastewater management system and ultimately, on the receiving waters. Consequently, a number of methods have been developed to analyse the performance of sewer systems with respect to I/I, including: distributed temperature sensing (DTS), closed-circuit television (CCTV) inspections, flow and conductivity measurements, automatic or grab sampling of ammonium, smoke testing, and visual inspection of manholes. Such methods were compared in an application to sanitary sewers in a small community and assessed with respect to their accuracy and ability to identify locations of sources of I/I, as well as temporal and spatial resolutions of the obtained results.

The quest for endothelial atypical cannabinoid receptor: BK channels act as cellular sensors for cannabinoids in in vitro and in situ endothelial cells.

Endothelium-dependent component of cannabinoid-induced vasodilation has been postulated to require G-protein-coupled non-CB/CB endothelial cannabinoid (eCB) receptor. GPR18 was proposed as a candidate for eCBR. To address the hypothesis that the effects attributed to eCBR are mediated by G-protein-coupled receptor (GPCR)-independent targets, we studied the electrical responses in endothelial cells, focusing on BK channels.

Ca-dependent potassium channels and cannabinoid signaling in the endothelium of apolipoprotein E knockout mice before plaque formation.

Endothelial Ca-dependent K channels (K) regulate endothelial function. We also know that stimulation of type 2 cannabinoid (CB) receptors ameliorates atherosclerosis. However, whether atherosclerosis is accompanied by altered endothelial K- and CB receptor-dependent signaling is unknown.

GPR55 agonist lysophosphatidylinositol and lysophosphatidylcholine inhibit endothelial cell hyperpolarization via GPR-independent suppression of Na-Ca exchanger and endoplasmic reticulum Ca refilling.

Lysophosphatidylinositol (LPI) and lysophosphatidylcholine (LPC) are lipid signaling molecules that induce endothelium-dependent vasodilation. In addition, LPC suppresses acetylcholine (Ach)-induced responses. We aimed to determine the influence of LPC and LPI on hyperpolarizing responses in vitro and in situ endothelial cells (EC) and identify the underlying mechanisms.

OMEGA-3 POLYUNSATURATED FATTY ACIDS NORMALIZE THE FUNCTION OF MITOCHONDRIA, ACTIVITY OF ENZYMES OF PROOXIDANT-ANTIOXIDANT SYSTEM AND THE EXPRESSION OF CYTOCHROME Р450 2Е1 AFTER ISOPROTERENOLINDUCED MYOCARDIAL INJURY.

We have studied the influence of dietary ω-3 polyunsaturated fatty acids (ω-3 PUFA) on the functioning of subsarcolemmal and interfibrillar mitochondrial fractions of rat myocardium, changes in expression of cytochrome P450 (CYP2E1) and the activity of enzymes of prooxidant-antioxidant system after isoproterenol-induced myocardial injury. It has been found that in vivo administration of ω-3 PUFA (Epadol 0.1 ml/100 gr of weight for 4 weeks) significantly reduced the swelling of subsarcolemmal and interfibrillar mitochondrial fractions by 65.

A linear functional strategy for regularized ranking.

Regularization schemes are frequently used for performing ranking tasks. This topic has been intensively studied in recent years. However, to be effective a regularization scheme should be equipped with a suitable strategy for choosing a regularization parameter.

[Prognostic Value of Hyperuricemia in Patients With Atrial Fibrillation and Heart Failure With Preserved Ejection Fraction].

Patients with permanent atrial fibrillation in comparison with cardiovascular patients without arrhythmia were found to have higher level of serum uric acid irrespectively of background of arterial hypertension and/or ischemic heart disease. Serum uric acid was shown to be an independent predictor of chronic heart failure exacerbation in atrial fibrillation patients.

Contamination of stormwater by wastewater: a review of detection methods.

Even in separate sewer systems, wastewater may find its way into the receiving waters through stormwater sewers. The main reasons for this are cross-connections, illicit connections, overflows and leakages through broken sewers. Such discharges may affect receiving water quality and increase risks to public health and aquatic organisms.

[The influence of dietary omega-3 polyunsaturated fatty acids on functional parameters of myocardial mitochondria during isoproterenol-induced heart injury].

We have studied the functional parameters of mitochondria from hearts after isopreterenol-induced injury (two subcutaneous injections of isopreterenol at the dose 60 mg/kg/day). We investigated the influence of dietary omega-3 polyunsaturated fatty acids (omega-3 PUFAs) administered to rats (Epadol, 0.1 mg/100 gr of weight for 4 weeks) on these parameters.

Omega-3 polyunsaturated fatty acid-enriched diet differentially protects two subpopulations of myocardial mitochondria against Ca(2+)-induced injury.

Omega-3 polyunsaturated fatty acids (PUFA) confer protection against myocardial injury after ischemia-reperfusion. There are two subfractions of mitochondria located in different regions of the cell: subsarcolemmal mitochondria (SSM) and interfibrillar mitochondria (IFM). The present study explored possible differences between Ca(2+)-induced mitochondrial swelling in rat SSM and IFM fractions under control conditions (control group [CG]) and after dietary supplementation with omega-3 PUFA (experimental group [EG]).

N-Arachidonoyl glycine suppresses Na⁺/Ca²⁺ exchanger-mediated Ca²⁺ entry into endothelial cells and activates BK(Ca) channels independently of GPCRs.

Background And Purpose: N-Arachidonoyl glycine (NAGly) is a lipoamino acid with vasorelaxant properties. We aimed to explore the mechanisms of NAGly's action on unstimulated and agonist-stimulated endothelial cells.

Experimental Approach: The effects of NAGly on endothelial electrical signalling were studied in combination with vascular reactivity.

Reduced hyperpolarization of endothelial cells following high dietary Na+: effects of enalapril and tempol.

1. High dietary Na(+) is associated with impaired vascular endothelial function. However, the underlying mechanisms are not completely understood.

[The results of a clinical trial of flurenizid in phthisiopulmonology practice].

Flurenizide, a new home drug preparation, endowed with antituberculosis activity, was administered to 20 patients with freshly detected pulmonary tuberculosis, in combination with etambutole or rifampycin in a daily dose of 0.6 g. After the above chemotherapy, closure of the cavities, diminution in size and consolidation of the foci as well as infiltrates, dispelling of the symptoms of intoxication, and discontinuance of bacteria discharge were observable in 70.

[The verification of amyloidosis by biopsies of the gastric and duodenal mucosa in patients with destructive tuberculosis and chronic nonspecific lung diseases].

Biopsy of the gastric and duodenal mucosa was carried out during diagnostic esophagogastroduodenofibroscopy. Histological examination was realized using the light polarization microscope. Amyloid was found in 48.

[The results of using a mathematical method for the differential diagnosis of pulmonary tuberculosis and cancer].

The authors developed a table differential-diagnostic algorithm designed for improvement of the differential diagnosis of pulmonary tuberculosis and cancer. This algorithm allows to establish precise diagnosis of cancer or tuberculosis of the lungs at district and regional health service levels, enhances the time of diagnosis and favours rational treatment.

Allelopathic influence ofSorghum bicolor on weeds during germination and early development of seedlings.

The allelopathic interaction between sorghum [Sorghum bicolor (L.) Moench] and 10 species of grass and broadleaf weeds was investigated. Germination of weed seeds was slightly inhibited or stimulated, depending on species, when incubated in closed Petri dishes with germinating sorghum.

Response of Colorado potato beetles,Leptinotarsa decemlineata (Say), to volatile components of tansy,Tanacetum vulgare.

The responses of Colorado potato beetle,Leptinotarsa decemlineata (Say), to volatile components of tansy,Tanacetum vulgare L., were investigated in order to establish a chemical basis for observed reduction in beetle populations when potatoes,Solanum tuberosum L., were interplanted with tansy.