Publications by authors named "Panagiotis Markopoulos"

Article Synopsis
  • Gastric adenomas are rare neoplastic lesions in the stomach, less common than other types of polyps, and often linked to mucosal atrophy and intestinal changes, with a risk for cancer development.
  • A case was reported involving a 66-year-old woman who was found to have a gastric adenoma during a routine procedure before surgery for an ovarian tumor.
  • Remarkably, her gastric adenoma showed spontaneous regression after 14 months, making it the first documented instance of this phenomenon without any medical intervention.
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  • Patients with inflammatory bowel disease (IBD) are at a higher risk for hepatitis B virus (HBV) and should ideally be vaccinated; this study evaluated the effectiveness of HBV vaccination among these patients and factors influencing their immune response.
  • A total of 409 IBD patients were studied, with 66.7% responding to the initial vaccination; those with lower body mass index had better immune responses, while certain disease types and treatments negatively impacted response rates.
  • Among nonresponders receiving revaccination, 58.3% achieved protective antibody levels, indicating that enhanced revaccination could benefit about half of these patients despite overall lower responsiveness compared to the general population.
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The present study shows how posterior malleolus fractures (PMFs) and distal fibular fractures were fixed using the posterolateral approach with the patient in lateral decubitus position, not previously described in the literature. This technique has been used in 60 consecutive patients (42 women and 18 men; mean age 54.7; range 21-92 years), 33 of which presented as fracture dislocations from March, 2021 to December, 2023.

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Article Synopsis
  • A study examined the effectiveness of biologic early prophylaxis for preventing endoscopic post-operative recurrence (ePOR) in Crohn's disease patients after ileocecal resection (ICR).
  • It included 297 patients and found that ePOR occurred in about 41.8% of cases within one year, with varying rates across treatment groups: 40.2% for anti-TNF, 33% for vedolizumab (VDZ), and 61.8% for ustekinumab (UST).
  • The results indicated no significant differences in ePOR risk between the anti-TNF therapy and the other biologics after adjusting for patient factors, suggesting early prevention was effective for around 60% of patients regardless of
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Background: Anemia is a common extraintestinal manifestation of Inflammatory Bowel Disease (IBD) affecting negatively the patients' quality of life. The aim of this study was to determine the frequency and real-life management of anemia in IBD patients in Greece.

Methods: This study was conducted in 17 Greek IBD referral centers.

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Background: Optimization of treatment with biologics is currently an unmet need for patients with ulcerative colitis (UC). Real-world studies provide neutral estimates of drug efficacy and safety within unselected patient populations and allow for the recognition of specific characteristics that affect response to therapy.

Aims: We aimed to depict the efficacy of vedolizumab in patients with UC in a real-world setting and identify prognosticators of improved outcomes.

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