Publications by authors named "Panagiotis Korkonikitas"
Background: Coronary computed tomography angiography (CCTA) in patients with post-coronary artery bypass graft (CABG) has a high diagnostic accuracy for visualization of grafts. Invasive coronary angiography (ICA) in patients with CABG is associated with increased procedural time, contrast agent administration, radiation exposure, and complications, compared with non-CABG patients. The aim of this multicenter, randomized controlled trial was to compare the strategy of CCTA-guided ICA versus classic ICA in patients with prior CABG.
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- Perivascular adipose tissue (PVAT) affects the vascular wall and releases factors that influence its physiology, while inflammation in the vascular wall alters the surrounding PVAT.
- Changes in pericoronary adipose tissue (PCAT) can be seen in coronary CT scans, specifically through an increase in fat attenuation, which is linked to coronary artery disease and its complications.
- A new imaging biomarker called Fat Attenuation Index (FAI) can improve cardiac risk assessment, but variability in measurement due to technical and biological factors is a concern, leading to the development of a medical device to standardize FAI values for clinical use.
Antiplatelet therapy including aspirin and thienopyridine agents (such as clopidogrel, prasugrel and ticagrelor) are often used in patients with coronary disease. Pulmonary hemorrhage due to antiplatelet therapy although very rare, when excessive, is a life-threatening event. So far, there is lack of specific guidelines for the management of these patients.
View Article and Find Full Text PDFIntroduction: Transvenous insertion of endocardial leads for permanent pacing is often accompanied by minor myocardial damage, detected thanks to the high sensitivity of cardiac troponins. It is unknown whether higher troponin levels, commensurate with more severe myocardial damage, can be encountered after implantation procedures.
Methods: Over a 3-year period, 283 patients underwent an implantation of a full antibradycardia pacemaker system (pulse generator plus leads).
Cell-free DNA that originates from cell death, circulates in peripheral blood. There are indications that the infarcted myocardium contributes to an increase of cell-free DNA levels. Our aims were to quantify levels of cell-free DNA in patients with acute myocardial infarction (AMI) and examine their correlation with myocardial markers and with postinfarction (PI) clinical course.
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