Adenosquamous carcinoma of the head and neck is a rare cancer associated with poor prognosis. Histologically, it is identified through the presence of both adenocarcinoma and squamous cell carcinoma, although it may be difficult to diagnose from initial endoscopic biopsies. We report a case of adenosquamous carcinoma of the glottis in an 82-year-old female patient who presented with progressive hoarseness of voice and in whom initial biopsies had shown only moderate to severe dysplasia.
View Article and Find Full Text PDFObjective: To estimate the frequency and strength of nocebo effects in trials for Menière disease (MD).
Data Sources: A literature search was conducted in PUBMED. The search terms we used were " Menière or Menière's," "treatment," and "placebo.
Objective: To assess outcomes with a novel passive transcutaneous bone conduction device (t-BCD).
Study Design: Prospective data collection and patient review.
Setting: Tertiary referral center.
JAMA Otolaryngol Head Neck Surg
September 2017
Importance: Eighty-five percent of investment in medical research has been wasted, with lack of effect on clinical practice and policy. There is increasing effort to improve the likelihood of research being used to influence clinical practice and policy. Tonsillectomy is one of the most common otorhinolaryngologic surgical procedures, and its frequency, cost, and morbidity create a clear need for evidence-based guidelines and policy.
View Article and Find Full Text PDFObjectives: To identify United Kingdom (UK)-specific research priorities in the field of bone conduction hearing devices (BCHDs).
Method: Narrative summary of the discussions and outcomes of a UK BCHD research workshop. The workshop was organized on 8 September 2016 under the auspices of the National Institute for Health Research (NIHR) Clinical Research Network (CRN) ENT Specialty group and Royal College of Surgeons (RCS) Clinical Research Initiative.
Int J Pediatr Otorhinolaryngol
March 2017
Objective: The aim of this study was to review the outcomes of Bone Anchored Hearing Aid (BAHA) Attract implantation in a cohort of paediatric patients.
Methods: Prospective data collection and case review were undertaken in a paediatric tertiary referral centre. We have included patients under the age of 16 years with unilateral or bilateral hearing loss that met the criteria for BAHA Attract implantation.
BMC Ear Nose Throat Disord
October 2016
Background: Bone conduction devices are widely used and indicated in cases of conductive, mixed or single sided deafness where conventional hearing aids are not indicated or tolerated. Percutaneous bone-conduction devices gave satisfactory hearing outcomes but were frequently complicated by soft tissue reactions. Transcutaneous bone conduction devices were developed in order to address some of the issues related to the skin-penetrating abutment.
View Article and Find Full Text PDFObjectives/hypothesis: Life-threatening ear, nose, and throat (ENT) emergencies are uncommon but require immediate skilled management. We investigated if traditional lecture-based teaching can be improved by a simulation and lecture hybrid approach.
Study Design: A single-blinded, prospective, randomized controlled trial.
A 22-year-old pregnant woman presented at the twenty-seventh week of gestation in the Emergency Department with acute abdominal pain and right iliac fossa tenderness. Urgent MRI was done and was suggestive of acute appendicitis. A laparoscopy was performed that confirmed an inflamed and purulent appendix that was removed.
View Article and Find Full Text PDFTorsion of the vermiform appendix is a rare disorder that causes symptoms similar to those of acute appendicitis. Primary and secondary causes of appendiceal torsion have been reported in the literature. Laparoscopy appears to be the most appropriate modality for diagnosis and treatment where the condition is suspected.
View Article and Find Full Text PDFBackground: Hearing loss in Paget's disease of bone (PDB) is typically mixed and bilateral. Although different mechanisms have been proposed, the pathophysiology of hearing impairment remains unclear.
Objective: The purpose of this study is to describe the histopathologic findings of temporal bones in patients with PDB and elucidate possible pathologic mechanisms related to hearing impairment.