One-year outcome of bevacizumab therapy for chronic macular edema in central and branch retinal vein occlusions in real-world clinical practice in the UK.

Background: The purpose of this study was to investigate the 12-month outcome of macular edema secondary to both chronic and new central and branch retinal vein occlusions treated with intravitreal bevacizumab in the real-life clinical setting in the UK.

Methods: Retrospective case notes analysis of consecutive patients with retinal vein occlusions treated with bevacizumab in 2010 to 2012. Outcome measures were visual acuity (measured with Snellen, converted into logMAR [logarithm of the minimum angle of resolution] for statistical calculation) and central retinal thickness at baseline, 4 weeks post-loading phase, and at 1 year.

Effect of initial retinal thickness on outcome of intravitreal bevacizumab therapy for diabetic macular edema.

Purpose: To investigate whether eyes with diabetic macular edema (DME) and central retinal thickness (CRT) >400 μm had better visual and anatomical outcomes compared to eyes with a CRT <400 μm when treated with intravitreal bevacizumab in a real-world setting.

Patients And Methods: Patients undergoing intravitreal bevacizumab therapy for DME were identified from the departmental database of a tertiary referral unit. Following the initial injection, a retreatment was performed for any persistent macular edema, unless there had been no previous response to repeated doses.

Clinical course and visual outcome in patients with diabetes mellitus and uveitis.

Purpose: We report the clinical course and visual outcome of patients with diabetes mellitus (DM) who subsequently developed uveitis from any cause.

Methods: Longitudinal, retrospective case note review.

Results: A total of 36 patients (M/F: 18/18, 58 eyes) were included, Of the 36 patients, 35 had Type 2 DM and one had Type 1 DM.

Late-stage metastasis to the choroid from follicular thyroid carcinoma--case report.

Background: Metastatic tumors to the choroid represent the most common uveal malignancy in adults. The most common origin of choroidal metastasis is from the breast and lung. Choroidal metastasis from thyroid carcinoma is rare.

Clinical features of patients with diabetes mellitus presenting with their first episode of uveitis.

Purpose: Little is known about uveitis in patients with diabetes mellitus (DM). The authors studied diabetic patients with their first episode of uveitis.

Methods: Cross-sectional, case note study documenting the uveitis, underlying cause/syndrome, treatment, type of DM and treatment, and any diabetic retinopathy.

Indocyanine green angiography in systemic lupus erythematosus-associated uveitis.

Purpose: To report indocyanine green (ICG) angiography findings in a patient with systemic lupus erythematosus-associated uveitis.

Methods: Review of the patient's clinical records.

Results: ICG angiography revealed dilatation of individual choroidal vessels in the early phase.

Bilateral combined retinal and choroidal detachment in antineutrophil cytoplasmic antibody-positive scleritis.

Purpose: To describe a rare complication of scleritis in a patient with positive serum antineutrophil cytoplasmic antibodies (ANCA).

Methods: We present a case report of a patient who developed bilateral retinal and choroidal detachment associated with ANCA-positive scleritis.

Results: Oral steroids alone were insufficient to maintain sustained remission of ocular inflammation.

Bilateral Coats' disease: long-term follow up.

Purpose: To report on the long-term follow-up of a female patient with bilateral Coats' disease, who showed marked asymmetry between the two eyes.

Methods: A five year old girl presented in 1978 with leukocoria in a blind right eye. A total exudative retinal detachment and extensive retinal telangiectasiae were noted.