Publications by authors named "Pan-Fei Hou"
Article Synopsis
- - The study explored the gut microbiota profiles in patients with esophageal cancer (EC) compared to healthy controls, finding that EC patients had higher microbial richness but similar evenness in their gut flora.
- - Significant differences in bacterial composition were observed, with increased levels of Firmicutes and Actinobacteria and decreased levels of Bacteroidetes in EC patients; specific genera like Streptococcus and Bifidobacterium were notably elevated in those with EC.
- - The research identified potential microbiota biomarkers for diagnosing EC, with ROC analysis indicating a high accuracy for certain bacteria, particularly Lachnospira, which may aid in future diagnosis and treatment strategies.
Thrombocytopenia may be caused by diseases of various organ systems, especially the blood system. Certain drugs may also cause thrombocytopenia. In addition, it can result from various causes of pseudo-reduction.
View Article and Find Full Text PDFDistribution of Carbapenemases and Efflux Pump in Carbapenem-resistance .
Ann Clin Lab Sci
March 2020
has emerged as an important pathogen related to serious infections and nosocomial outbreaks around the world. In this study, 100 isolates of carbapenem-resistance in (CRAB) were collected from clinical specimens. Agar dilution was conducted to determine the minimum inhibitory concentrations (MICs) for 15 kinds of antibiotics.
View Article and Find Full Text PDFBudding uninhibited by benzimidazoles 1 (BUB1) is a mitotic checkpoint serine/threonine kinase that has been reported as an oncogene or tumor suppressor gene in various types of cancer, including breast cancer, pancreatic ductal adenocarcinoma, prostate and gastric cancers. However, its role in liver cancer remains unclear. The present study aimed to explore the biological function of BUB1 in liver cancer.
View Article and Find Full Text PDFObjective: Acinetobacter baumannii has become an important problem because of the high drug resistance rate. The aim of this study was to assess the antimicrobial resistance profile and explore the role of membrane porin in imipenem resistance of A baumannii.
Methods: A total of 63 isolates of imipenem-resistant A baumannii (IRAB) and 21 of imipenem-sensitive A baumannii (ISAB) were collected.
Objectives: CD4+CD25+FOXP3+ regulatory T cells (Treg) inhibit the anti-tumour immune response and reduce the effect of cancer immunotherapy. Although studies have demonstrated that the number and suppressive activity of Treg increase with age, it is not clear whether these changes correlate with a higher incidence of tumours in the elderly. This study was designed to explore the relationship between increase in CD4+CD25+FOXP3+ Treg and the higher risk of lung cancer in the elderly.
View Article and Find Full Text PDFBackground: To investigate the role of efflux pumps AdeABC, AdeIJK, AdeDE and AbeM in reduced susceptibility to imipenem in clinical isolates of Acinetobacter baumannii.
Methods: Susceptibility testing was conducted by the agar dilution method. The presence and expression of pump genes were analyzed by conventional PCR and real-time RT-PCR, respectively.