Codon usage characteristics of PB2 gene in influenza A H7N9 virus from different host species.

The influenza A H7N9 virus is a highly contagious virus which can only infect poultry before early 2013. But after that time, it widely caused human infections in China and brought Southeast Asia great threaten in the public health area. The coding gene for polymerase basic protein 2 (PB2) in influenza A H7N9 virus encodes the PB2 protein, which is a part of the RNA polymerase.

Comprehensive Analysis and Comparison on the Codon Usage Pattern of Whole Coding Genome from Different Area.

Phenomenon of unequal use of synonymous codons in is common. Codon usage bias not only plays an important regulatory role at the level of gene expression, but also helps in improving the accuracy and efficiency of translation. Meanwhile, codon usage pattern of genome is important for interpreting evolutionary characteristics in species.

Beta-catenin mediates the apoptosis induction effect of celastrol in HT29 cells.

Aim: We evaluated the apoptosis induction effects of celastrol in human colorectal cancer cell line HT29 in WNT/beta-catenin pathway.

Main Methods: HT29 cells were treated with various concentrations (10-100μM) for 24h, MTT assay was performed to examine the effect of celastrol on growth inhibition of HT29 cells. Beta-catenin siRNA was used for transfection of cells.

Design and experiment of a neural signal detection using a FES driving system.

The channel bridging, signal regenerating, and functional rebuilding of injured nerves is one of the most important issues in life science research. In recent years, some progresses in the research area have been made in repairing injured nerves with microelectronic neural bridge. Based on the previous work, this paper presents a neural signal detection and functional electrical stimulation (FES) driving system with using high performance operational amplifiers, which has been realized.

Curve fitting of spikes in neural signals.

Unlabelled: Find an optimal function model of spikes of high signal-to-noise ratio (SNR) spontaneous signals in the spinal cord of a rat, and use it to recognize the patterns of spikes of low SNR signals in the sciatic nerve of the rat.

Method: Firstly, several function models of spikes of high SNR spontaneous signals in the spinal cord of a rat are calculated under the rule of least square. By choosing an optimal function model based on minimum standard deviation (SD) of error of fitting, it is contrasted with the waveform of classical action potential (AP).