Publications by authors named "Pamella B Tijerina"
Article Synopsis
- Exposure to fine ambient particulates (PM) during pregnancy and early life has significant neurotoxic effects, potentially influencing behaviors linked to autism spectrum disorders (ASD).
- A study on BCF mice showed that perinatal exposure to concentrated ambient PM led to reduced sociability and increased repetitive behaviors, traits often associated with ASD.
- The results indicated that male mice exhibited more pronounced behavioral changes compared to females, suggesting that early exposure to air pollution could contribute to the development of neurodevelopmental disorders like ASD in a sex-dependent way.
Frontal Cortex Transcriptome Analysis of Mice Exposed to Electronic Cigarettes During Early Life Stages.
Int J Environ Res Public Health
April 2016
Electronic cigarettes (e-cigarettes), battery-powered devices containing nicotine, glycerin, propylene glycol, flavorings, and other substances, are increasing in popularity. They pose a potential threat to the developing brain, as nicotine is a known neurotoxicant. We hypothesized that exposure to e-cigarettes during early life stages induce changes in central nervous system (CNS) transcriptome associated with adverse neurobiological outcomes and long-term disease states.
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