Corneal ectasia and high ametropia in an infant with microcephaly associated with presumed Zika virus congenital infection: new ocular findings.

We report the first case of a corneal ocular ectasia in an infant with Zika virus congenital infection (CZS). We suspect that the ocular embryology and neurotropism of the Zika virus could account for the corneal involvement.

Clinical Characteristics and Prognosis in Children and Adolescents With Autoimmune Hepatitis and Overlap Syndrome.

Objectives: This is a cohort study of 134 children and adolescents with a known diagnosis of autoimmune hepatitis (AIH). During follow-up, some of them developed autoimmune sclerosing cholangitis (ASC). This study describes the characteristics of the patients upon diagnosis, and their response to treatment and any complications, and compares the patients who developed ASC during follow-up (ASC group) with those who did not (AIH group).

Nutritional evaluation of children with chronic cholestatic disease.

Objective: To evaluate the nutritional status of children with persistent cholestasis and to compare the anthropometric indices between children with and without liver cirrhosis and children with and without jaundice.

Methods: Children with persistent cholestasis, i.e.