Publications by authors named "Pamela S Puttfarcken"
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Synopsis of recent research by authors named "Pamela S Puttfarcken"
- Pamela S Puttfarcken's research primarily focuses on the transient receptor potential vanilloid (TRPV) channels, particularly TRPV1 and TRPV3, investigating their roles in thermoregulation, pain sensation, and potential therapeutic applications.
- Recent studies have led to the identification of selective TRPV1 antagonists that exhibit unique thermoregulatory profiles, with some compounds demonstrating analgesic efficacy without causing hyperthermia, highlighting their potential for pain management without adverse side effects.
- Puttfarcken's work also includes the exploration of novel compounds targeting alpha7 nicotinic acetylcholine receptors, which are implicated in cognitive function, suggesting a broader interest in both pain modulation and cognitive enhancement through receptor-specific pharmacology.