Publications by authors named "Pamela S Lancaster"
Article Synopsis
- The study aimed to evaluate the effects of the drug suberoylanilide hydroxamic acid (SAHA) alone and in combination with paclitaxel on ovarian cancer cells and in a mouse model.
- Results showed that while both SAHA and paclitaxel reduced cancer cell viability and increased apoptosis, their combination did not provide significant additional benefits; however, the order of administration affected survival rates in mice.
- Overall, the findings suggest that using SAHA alongside paclitaxel could enhance chemotherapy effectiveness in ovarian cancer, emphasizing the importance of drug sequencing in treatment.
