Effect of Treatment with Selective Caries Removal Associated to Antimicrobial Photodynamic Therapy on Children's Oral Health-Related Quality of Life: A Non-Randomized Clinical Study.

Unlabelled: How patients perceive impact of diseases is an essential component when characterising different disease impacts, and effects of dental treatments should be perceived by the patients. This study aimed to assess the impact of conservative treatment of deep caries lesions using the selective caries removal (SCR) associated to a low laser therapy (antimicrobial photodynamic therapy-aPDT) on oral health-related quality of life (OHRQoL).

Study Design: A non-randomized clinical before-and-after study was conducted on children aged 4 to 8 years.

Virulence of spp. misidentified as from children's carious dentine.

This study aimed to search for in children's deep carious dentine and characterize their virulence traits. Eight isolates from 15 carious molars identified by 16S rDNA species-specific PCR as were included. These eight isolates were subject to identification by MALDI-TOF and characterized regarding: (i) bacterial aggregation and biofilm formation on polystyrene and glass, with/without saliva, as single or dual-species (associated to ); (ii) environmental pH measurement before and after 24 h incubation; (iii) acidogenicity; (iv) gelatinase production; (v) macrophage adherence; and (vi) toxicity towards .

Use of antimicrobial photodynamic therapy for treatment of deep caries in the primary dentition: a step-by-step technique report.

Antimicrobial photodynamic therapy (aPDT) is increasingly used in dentistry to treat a number of diseases. The procedure involves the activation of a photosensitizer by a visible light source to induce chemical reactions that create cytotoxic reactive oxygen species, cause oxidative stress, and result in inactivation of pathogenic microorganisms. The use of aPDT has been proven to reduce microorganisms present in dentin and therefore may be effective for treatment of deep caries.

Effect of the antimicrobial photodynamic therapy on microorganism reduction in deep caries lesions: a systematic review and meta-analysis.

This study aimed to perform a systematic review to assess the effectiveness of antimicrobial photodynamic therapy (aPDT) in the reduction of microorganisms in deep carious lesions. An electronic search was conducted in Pubmed, Web of Science, Scopus, Lilacs, and Cochrane Library, followed by a manual search. The MeSH terms, MeSH synonyms, related terms, and free terms were used in the search.