Publications by authors named "Pamela M Lindholm"
Malignant mesothelioma (MM) is an aggressive cancer arising from mesothelial cells, mainly due to former asbestos exposure. Little is known about the microRNA (miRNA) expression of MM. miRNAs are small noncoding RNAs, which play an essential role in the regulation of gene expression.
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- Asbestos exposure is linked to serious lung diseases and causes chromosomal and DNA damage, though the underlying mechanisms are still unclear.
- Researchers exposed human cell lines to asbestos and analyzed gene expression changes over time to identify affected genes and biological processes.
- The study discovered several known and new genes related to asbestos responses, highlighting potential targets for further research into asbestos-related diseases.