Publications by authors named "Pamela M Hannigan"
Article Synopsis
- Hyperbaric oxygen (HBO) therapy is gaining attention for treating conditions beyond its established uses, particularly due to its effects on hypoxia and inflammation.
- A web-based International Multicenter Registry collects data from various centers to analyze HBO treatment outcomes and identify new potential applications across different medical specialties.
- The study found that out of 9,726 patients, 378 were treated for 45 new indications, with a significant number related to post-COVID-19 conditions, ulcerative colitis, and Crohn's disease.
Introduction: The International Multicenter Registry for Hyperbaric Oxygen Therapy (International Report Registered Identifier DERR1-10.2196/18857) was established in 2011 to capture outcomes and complications data for both Undersea and Hyperbaric Medical Society (UHMS) approved and selected unapproved hyperbaric oxygen (HBO2) therapy indications.
Methods: A Research Electronic Data Capture (REDCap) template was designed and distributed to all participating centers for prospective data collection.
Background: Hyperbaric oxygen (HBO)-oxygen at pressures higher than atmospheric-is approved for 14 indications by the Undersea and Hyperbaric Medical Society. HBO's main effect is to increase oxygen content in plasma and body tissues, which can counteract hypoxia or ischemia. Laboratory studies show that HBO has effects beyond relieving hypoxia (eg, promoting angiogenesis in irradiated tissue, anti-inflammatory effects, radiosensitization of tumors, hypoxia preconditioning, and fungal growth inhibition) and has potential to treat conditions such as inflammatory bowel disease and pyoderma gangrenosum.
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