Effects of desmopressin acetate administration in healthy dogs receiving prednisolone.

Background: Glucocorticoids are used for a variety of purposes in veterinary medicine but often are associated with clinically important adverse effects. Polyuria and polydipsia are the most frustrating adverse effects noted by owners.

Objective: To determine whether administration of desmopressin ameliorates polyuria and polydipsia associated with prednisolone administration.