Publications by authors named "Pamela C L G Valente"

Lymphoma ranks among the most prevalent neoplasms in veterinary oncology, frequently diagnosed in dogs, particularly in its multicentric form. While histopathology plays a crucial role in lymphoma diagnosis, prognosis and prediction of biological behavior, minimally invasive diagnostic methods are increasingly emerging as viable alternatives. This study aims to assess and compare various minimally invasive diagnostic techniques for multicentric lymphomas in dogs.

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Background: The diagnosis of multiple myeloma (MM) in dogs may be challenging and complex. The cell blocks are a diagnostic technique that allows the characterization of neoplastic cells and, therefore, might help in the diagnosis of atypical MM.

Objective: The objective of the present work is to describe three clinical cases in which the cell blocks and immunohistochemistry contributed to the definitive diagnosis of canine MM.

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Article Synopsis
  • An 8-year-old spayed female Labrador retriever was referred for a second opinion due to persistent vomiting and lethargy, showing abnormal blood results like high bilirubin and low albumin levels.
  • Imaging techniques, including abdominal ultrasound and biopsies, revealed thickening of the intestines and liver enlargement, leading to concerns of lymphoma.
  • Ultimately, the diagnosis confirmed type 2 enteropathy-associated T-cell lymphoma with liver involvement, as indicated by both cytological examinations and immunohistochemical studies showing abnormal lymphocyte activity.
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The recent emergence of a new myxoma virus capable of causing disease in the Iberian hare () has resulted in numerous outbreaks with high mortality leading to the reduction, or even the disappearance, of many local populations of this wild species in the Iberian Peninsula. Currently, the available vaccines that prevent myxomatosis in domestic rabbits caused by classic strains of myxoma virus have not been assessed for use in Iberian hares. The main objective of this study was to evaluate the efficacy of commercial rabbit vaccines in Iberian hares and wild rabbits against the natural recombinant myxoma virus (ha-MYXV), bearing in mind its application in specific scenarios where capture is possible, such as genetic reserves.

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Information on Anaplasma phagocytophilum in Brazil is very restricted. The aim of this study was to report clinical, parasitological, hematological and molecular evidence of a natural A. phagocytophilum infection of an urban Brazilian dog.

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