Applicability of the External Genitalia Score (EGS) in Indian neonates and children up to 2 years of age.

Objectives: To generate normative data and validate the recently developed, gender-neutral, External Genitalia Score (EGS) in Indian preterm and term neonates and children up to 2 years of age with normal and atypical genitalia.

Methods: This observational study included 1,040 neonates born between 28 and 42 weeks of gestation and 152 children between 1 and 24 months of age. In addition, 50 children with disorders of sex development (DSD) were also enrolled in the study.

Cognitive Function in Early Onset Type 1 Diabetes in Children.

Objectives: To assess cognitive function and factors affecting it in Indian children with early-onset type 1 diabetes (T1D) (less than 6 y).

Methods: This cross-sectional, single-centre study recruited children diagnosed with T1D before 6 y of age and having a disease duration of at least 2 y, as cases. Controls were age- and sex-matched apparently healthy children or siblings.

Estimation of Reference Values for External Genitalia Parameters in North Indian Preterm and Term Female Newborns.

Objectives: To establish gestation-wise normative data of external genitalia measurements in North Indian term and preterm female newborns.

Methods: In this cross-sectional descriptive study, institutionally-born female neonates between 28-42 wk gestation were consecutively enrolled between 24-72 h of life. Newborns with major congenital malformations, chromosomal anomalies, multifetal gestation and birth injuries were excluded.

Estimation of Reference Values for External Genitalia Parameters in North Indian Preterm and Term Male Newborns.

Objectives: To generate gestation-wise normative data of external genitalia measurements in North Indian term and preterm male newborns.

Methods: This was a hospital-based cross-sectional observational study. Male neonates born between 28-42 wk of gestation (at 24-72 h of life) were consecutively recruited in the study.

Tolvaptan for Treatment of Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH) in a Child with Corpus Callosum Agenesis.

Syndrome of inappropriate antidiuretic hormone secretion (SIADH) is one of the common causes of euvolemic hyponatremia (serum Na < 135 mEq/L) in hospitalized children. It is characterized by increased serum ADH, leading to water retention via its action on V2 receptors in the distal renal tubules. Various conditions such as pain, the postoperative state, drugs, central nervous system infections, tumors, malformations, and pneumonia can predispose a person to SIADH.

Stem cell therapy for type 1 diabetes: a scientometric assessment of global research during the twenty-first century.

Purpose: We aimed to provide a scientometric assessment of global research in stem cell therapy (SCT) for type 1 diabetes (T1D) during 1999-2020.

Methods: The published data on SCT in T1D were retrieved from Elsevier's Scopus database and analyzed using select bibliometric tools. We used VOSviewer software and the Biblioshiny app to construct and visualize bibliometric networks.

Molecular Characterization and Management of Congenital Hyperinsulinism: A Tertiary Centre Experience.

Background: There is limited data from India regarding medical management of congenital hyperinsulinism (CHI).

Objective: To study the molecular diagnosis, medical management and outcomes of children with CHI.

Study Design: Ambispective.

Bartter syndrome and hypothyroidism masquerading cystinosis in a 3-year-old girl: rare manifestation of a rare disease.

Cystinosis is a multisystem disorder with varied presentations secondary to deposition of cystine crystals in different organ systems. Children with cystinosis typically present with renal tubular acidosis and failure to thrive. We report a 3-year-old girl, born to a third-degree consanguineous couple, who presented with failure to thrive and polyuria.