Pyroglutamyl-peptidase I: cloning, sequencing, and characterisation of the recombinant human enzyme.

Pyroglutamyl-peptidase I (EC 3.4.19.

Inhibition of mammalian legumain by Michael acceptors and AzaAsn-halomethylketones.

Legumain is a lysosomal cysteine peptidase specific for an asparagine residue in the P1-position. It has been classified as a member of clan CD peptidases due to predicted structural similarities to caspases and gingipains. So far, inhibition studies on legumain are limited by the use of endogenous inhibitors such as cystatin C.