A contact binary satellite of the asteroid (152830) Dinkinesh.

Asteroids with diameters less than about 5 km have complex histories because they are small enough for radiative torques (that is, YORP, short for the Yarkovsky-O'Keefe-Radzievskii-Paddack effect) to be a notable factor in their evolution. (152830) Dinkinesh is a small asteroid orbiting the Sun near the inner edge of the main asteroid belt with a heliocentric semimajor axis of 2.19 AU; its S-type spectrum is typical of bodies in this part of the main belt.

An acute rat in vivo screening model to predict compounds that alter blood glucose and/or insulin regulation.

Introduction: Drug-induced glucose dysregulation and insulin resistance have been associated with weight gain and potential induction and/or exacerbation of diabetes mellitus in the clinic suggesting they may be safety biomarkers when developing antipsychotics. Glucose and insulin have also been suggested as potential efficacy biomarkers for some oncology compounds. The objective of this study was to qualify a medium throughput rat in vivo acute Intravenous Glucose Tolerance Test (IVGTT) for predicting compounds that will induce altered blood glucose and/or insulin levels.

Inhibition of oestradiol-induced prolactin release in a dual-cannulated ovariectomized rat model by carmoxirole, a peripherally restricted dopamine agonist.

Centrally acting dopamine agonists (e.g. bromocriptine) and dopamine transport inhibitors (e.

Identifying the development needs of community matrons.

Aim: To gain some insight into the needs of community matrons from both the practitioners' and managers' perspectives.

Method: Focus groups with community matrons in different PCTs.

Results: The focus groups identified that skills in physical assessment and prescribing were taken as prerequisites or essential to the role, and that the educational priorities were viewed as clinical education relating to the management of many long-term conditions linked to major causes of unplanned admissions.

Nurse prescribers: who are they and how do they perceive their role?

Aims: This paper reports a study to elicit background data from recently qualified nurse prescribers and explore aspects of their work.

Background: Nurse prescribing has been introduced quite recently in the United Kingdom. Although a certain amount of information is available about the characteristics of nurse prescribers, relatively little is known about their professional backgrounds, their reasons for choosing to become nurse prescribers and their perceptions of their emerging role.