Publications by Palukuri Srivani

Publications by authors named "Palukuri Srivani"

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Strategies to design pyrazolyl urea derivatives for p38 kinase inhibition: a molecular modeling study.

Ravindra G Kulkarni Palukuri Srivani Garlapati Achaiah G Narahari Sastry

J Comput Aided Mol Des

April 2007

The p38 protein kinase is a serine-threonine mitogen activated protein kinase, which plays an important role in inflammation and arthritis. A combined study of 3D-QSAR and molecular docking has been undertaken to explore the structural insights of pyrazolyl urea p38 kinase inhibitors. The 3D-QSAR studies involved comparative molecular field analysis (CoMFA) and comparative molecular similarity indices (CoMSIA).

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