The overlap with metabolic dysfunction-associated steatotic liver disease negatively affects outcomes of primary biliary cholangitis.

Background And Aims: The relationship between primary biliary cholangitis (PBC) and metabolic dysfunction-associated steatotic liver disease, and its impact on treatment response and prognosis, remains underexplored.

Methods: Patient cohort from two centres comprising long-term follow-up data. All patients had histologically confirmed PBC.

The loss of crude oil droplets by filter feeders and the role of surfactants.

Various methods of oil spill remediation exist, e.g., floating booms, controlled burning and the release of chemical surfactants.

Subcutaneous atypical fibrous histiocytoma.

Benign fibrous histiocytoma is one of the most frequent benign neoplasms mainly composed of a mixture of fibroblastic and histiocytic cells, especially found in the skin (dermatofibroma), particularly in the limbs. The diagnosis of cutaneous benign fibrous histiocytoma is generally easy; however, rare variants may be difficult to identify, and the diagnosis only confirmed after exhaustive histopathological examination. Thus, deep subcutaneous dermatofibroma may be difficult to distinguish from dermatofibrosarcoma protuberans and dermatofibroma with monster giant cells from malignant fibrous histiocytoma and atypical fibroxanthoma.

[Variation in the prognostic value of p53 protein in relation to tumoral stage in patients with colorectal adenocarcinoma].

Objective: To analyze the prognostic value of p53 protein as a marker of recurrence risk in each tumoral stage.

Patients And Method: A prospective study of a cohort of 288 patients who underwent surgery for colorectal adenocarcinoma was performed. Stage 1 of the tumor-node-metastasis (TNM) classification was found in 42 patients (14.