Publications by authors named "Paloma Garcia Clemente"
Severe Impairment of T-cell Immunity and Pulmonary GvHD Are Major Risk Factors for Nontuberculous Mycobacterial Infection After Pediatric Allogeneic Hematopoietic Stem Cell Transplantation.
Pediatr Infect Dis J
September 2024
Article Synopsis
- Pediatric hematopoietic stem cell transplant recipients are at high risk for infections, particularly nontuberculous mycobacteria.
- A study reports six cases of disseminated or pulmonary infections in five children, mostly caused by Mycobacterium avium complex.
- Out of the five patients, four died, with two deaths directly linked to the mycobacterial infections.
Comparison of gradient diffusion and molecular methods using Allplex™ NG&DR assay (Seegene®) for macrolide and fluoroquinolone screening resistance in Neisseria gonorrhoeae.
Eur J Clin Microbiol Infect Dis
May 2024
Article Synopsis
- * The study compared a gradient diffusion test to a new molecular method (Allplex™ NG&DR assay) for detecting mutations linked to resistance in 100 NG isolates, finding no significant correlation for fluoroquinolone resistance but identified a high rate of S91F mutations.
- * While the molecular method showed good sensitivity (96.1%) and specificity (90.9%) for fluoroquinolone resistance, it cannot replace the gradient diffusion test for macrolides due to lack of positive results for resistance mutations.
osteomyelitis is a rare complication of extrapulmonary invasive aspergillosis, which usually presents as spondylodiscitis. The clinical picture is usually paucisymptomatic and of long evolution, which leads to diagnostic difficulties, especially in immunosuppressed patients presenting a delayed systemic host response. We report a case of femoral osteomyelitis caused by in a heart transplant recipient successfully treated with a combined surgical and antifungal approach.
View Article and Find Full Text PDFDetection and characterization of two methicillin- and cefoxitin-susceptible mecA Staphylococcus aureus isolates from blood cultures of two adult patients.
J Glob Antimicrob Resist
December 2022
The SARS-CoV-2 pandemic might have increased the risks of healthcare-associated infections (HAIs); however, several studies of HAI such as urinary tract infections (UTIs) and catheter-associated urinary tract infections (CAUTIs) have shown contradictory results. The aim of this study is to assess the clinical features of UTIs and bacterial isolates from urine samples of hospitalized COVID-19 patients. We conducted a retrospective observational study including 87 COVID-19 patients with UTIs admitted to our centre.
View Article and Find Full Text PDFBackground: Real-time reverse transcription-quantitative polymerase chain reaction (RT-qPCR) is the reference laboratory method to diagnose SARS-CoV-2 infection then requires equipment and is time-consuming. There is a crucial demand for rapid techniques such as antigen detection test. Considering the different diagnostic accuracy of tests with other respiratory viruses in adults and children, SARS-CoV-2 antigen test must be evaluated specifically in children.
View Article and Find Full Text PDFThe FilmArray Meningitis/Encephalitis Panel detects the 14 most frequent pathogens causing meningitis and/or encephalitis. The use of FilmArray ME with non-validated samples is seldom published in the literature. We describe the case of a 3-year-old child, diagnosed with acute meningoencephalitis, in whom the FilmArray ME technique successfully identified Neisseria meningitidis in both skin biopsy and whole blood samples.
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