Publications by authors named "Pallobi Ray"
Fenugreek () is a widely grown dietary herb in Asia, and its seeds are traditionally used for several diseases, including diabetes. The seeds and leaves possess a variety of compounds that play an important role in regulating their hypoglycemic effect. However, so far, no extensive systematic review exists on its antidiabetic effect, highlighting the molecular mechanisms and isolated compounds.
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- - The study investigates the potential anticancer effects of two alkaloids, Chabamide F and Chabamide G, derived from a traditional medicinal plant, Piper chaba, particularly focusing on their mechanisms against breast cancer (BC).
- - Using in silico methods, researchers identified 64 BC-related genes and found that key biological pathways, including RAS and PI3K-AKT, are heavily linked to the effects of the alkaloids on tumor growth and spread.
- - Molecular docking suggests that Chabamide F and G have strong binding affinities for critical proteins (SRC and AKT1) involved in breast cancer, indicating potential therapeutic benefits, especially with G showing significantly higher binding energies than control drugs. *