Drag Reduction Using Polysaccharides in a Taylor⁻Couette Flow.

Three different polysaccharides, aloe vera, Tamarind powder and pineapple fibers, are utilized as drag reducing agents in a turbulent flow. Using a Taylor⁻Couette setup, consisting of a rotating inner cylinder, for measuring the drag reduction, a range of Reynolds numbers from 4 × 10⁴ to 3 × 10⁵ has been explored in this study. The results are in good agreement with previous studies on polysaccharides conducted in a pipe/channel flow and a maximum drag reduction of 35% has been observed.

Design and pharmaceutical applications of a low-flow-rate single-nozzle impactor.

A new low-flow-rate (0.5L/min) single-nozzle impactor for the concentration of dilute aerosol particles with selected pharmaceutical applications is described in this paper. The impactor can be configured up to 11 stages with a wide range of cutoff diameters from 0.

Humidity affects the morphology of particles emitted from beclomethasone dipropionate pressurized metered dose inhalers.

The effects of propellant type, cosolvent content, and air humidity on the morphology and solid phase of the particles produced from solution pressurized metered dose inhalers containing the corticosteroid beclomethasone dipropionate were investigated. The active ingredient was dissolved in the HFA propellants 134a and 227ea with varying levels of the cosolvent ethanol and filled into pressurized metered dose inhalers. Inhalers were actuated into an evaporation chamber under controlled temperature and humidity conditions and sampled using a single nozzle, single stage inertial impactor.

Verapamil eluting stents as a possible treatment for vasospasm after subarachnoid hemorrhage.

Objective: The only pharmacologic prophylaxis for cerebral vasospasm after subarachnoid hemorrhage is oral nimodipine. A novel way to mitigate this risk may be to design a drug eluting stent that elutes verapamil over the time period typically associated with vasospasm. In this study, we explore different methods of coating nitinol stents with a bioabsorbable polymer and determine the release profile of various verapamil coated stents for the potential treatment of vasospasm.