The role of modern parameters and their relationship with recurrence risk as assessed by Oncotype DX: real-world evidence.

Genomic analysis through various platforms is an essential tool for determining prognosis and treatment in a significant subgroup of early-stage breast cancer patients with hormone receptor-positive and human epidermal growth factor receptor 2 (HER2)-negative status. Additionally, combined clinical and pathological characteristics can accurately predict the recurrence score (RS), as demonstrated by the University of Tennessee risk nomogram. In this study, we aimed to identify classical clinical-pathological factors associated with high RS in a local population, including modern parameters such as current abemaciclib treatment recommendations, HER2-low status, different Ki-67 cutoff values, and samples obtained from secondary primary tumours.

The Emerging Role of Tertiary Lymphoid Structures in Breast Cancer: A Narrative Review.

This narrative review aims to clarify the role of tertiary lymphoid structures in breast cancer. We examine their development, composition, and prognostic value, and current ways of recognizing them. A comprehensive literature review was performed using the PubMed/Medline, Scopus, and EMBASE databases.

Constructing Integrable Lindblad Superoperators.

We develop a new method for the construction of one-dimensional integrable Lindblad systems, which describe quantum many body models in contact with a Markovian environment. We find several new models with interesting features, such as annihilation-diffusion processes, a mixture of coherent and classical particle propagation, and a rectified steady state current. We also find new ways to represent known classical integrable stochastic equations by integrable Lindblad operators.

Classifying Nearest-Neighbor Interactions and Deformations of AdS.

We classify all regular solutions of the Yang-Baxter equation of eight-vertex type. Regular solutions correspond to spin chains with nearest-neighbor interactions. We find a total of four independent solutions.

Prolonged success with a covered endovascular stent after emergent use in radiation-induced subclavian artery blowout: a case report.

Radiation-induced damage to the bone, soft tissues, and vasculature represents the unfortunate consequences of radiation therapy for the treatment of malignant tumors. Complications arising from irradiation are frequently challenging to manage and may be life threatening. A case is presented of a patient with a longstanding clavicular osteoradionecrosis with an acute massive hemorrhage after rupture of the subclavian artery and subsequent management with endovascular stent placement.

Liposuction as an adjunct procedure in reduction mammaplasty.

Liposuction has been recognized as a useful adjunct to breast reduction surgery for fine contouring of adjacent areas to achieve aesthetic balance and preservation of nipple sensation. In particular, the liposuction technique has provided an acceptable way of treating the "fat roll" of the lateral portion of the breast, which extends to the axilla and lateral chest. The purpose of this study was to review the authors' approach to adjunctive lipoplasty with breast reduction surgery and to review their experience.

Major leg wound complications after saphenous vein harvest for coronary revascularization.

Background: Major leg wound complications after coronary artery bypass graft procedures are infrequent and few are reported in the literature. We present our experience in treating 23 patients with major leg wound complications after coronary revascularization procedures.

Methods: A retrospective review of 3,525 bypass procedures with saphenous vein grafts performed over a 10-year period was conducted.

Granular cell tumor in a child's finger.

Granular cell tumor is an uncommon tumor found in the hand. It is probably of Schwann cell origin and may be associated with a peripheral nerve. Although it is often described as a painless tumor of the oral cavity and skin, its presentation in the fingers or hand is often painful--a characteristic not well recognized.

An unusual presentation of constriction band syndrome.

Congenital constriction band syndrome is a rare entity with a wide spectrum of associated congenital anomalies. Review of the pathogenesis and an unusual case of constriction band syndrome in a newborn are presented. Surgical excision of the deformity and the band was performed within the first week of life.

Intrathoracic application of the reverse latissimus dorsi muscle flap.

The use of the reverse latissimus dorsi muscle flap based on its paraspinous perforators for posterior trunk wound coverage has been described previously. However, few studies have reported its intrathoracic application. In this study the authors present their experience in treating 3 patients with various intrathoracic defects using the reverse latissimus dorsi muscle flap.

Reconstructive surgery in children after meningococcal purpura fulminans.

Background/purpose: Purpura fulminans (PF) is a serious, often life-threatening disease. As more children are surviving their disease, surgeons are presented with increasing numbers of multiple and complicated wounds as sequelae of PF. The purpose of this paper is to review the management of nine cases of PF, and present the reconstruction method in treating bilateral exposed elbow and knee joints.

The use of tissue expanders in staged abdominal wall reconstruction.

Reconstruction of large abdominal wall defects not amenable to primary closure remains a challenging problem. Various reconstructive techniques have been described in the surgical literature each with its advantages and disadvantages. In this report the authors describe their experience in treating 11 patients with large abdominal wall defects utilizing prosthetic mesh in conjunction with tissue expanders.

Surgical management of large breast tumors in the adolescent.

The management of adolescent females with giant cystosarcoma phylloides remains controversial. Since in this age group the overwhelming majority of these neoplasms are benign, aesthetic outcome is as important as adequate tumor resection. Traditional, treatment has been wide local excision, which may lead to substantial breast deformity.

Internal pudendal flap anoplasty for severe anal stenosis. Report of a case.

Purpose: A technique for introducing anoderm into the anal canal is described.

Methods: An internal pudendal flap was used.

Results: This technique was totally successful in alleviating anal stenosis and maintaining fecal continence.

Epithelialization of the lining of a breast implant capsule. Possible origins of squamous cell carcinoma associated with a breast implant capsule.

The authors described a case in which the capsule surrounding a breast implant was lined by benign squamous epithelium. A second case, in which a woman was found to have a squamous cell carcinoma in the capsule surrounding a breast implant, was also reported.

Compartment syndrome in children.

The development of compartment syndrome is a well-recognized clinical entity. The diagnosis and management of compartment syndrome in the adult population is well established. Because of the difficulty with cooperation in physical examination of children with pain, the early recognition of compartment syndrome in this group of patients can be more challenging.

[Immune complex glomerulonephritis associated with pulmonary tuberculosis].

A 32 year old man was admitted for dyspnea, hemoptysis, macroscopic hematuria, hypertension (140/100), peripheral edema and hemodynamic decompensation. Lung Xrays revealed pulmonary edema and a cavity in the left apex. Laboratory determinations revealed an altered renal function with increased creatinine and urea levels and nephrotic syndrome.

Viability of the rectus abdominis muscle following internal mammary artery ligation.

The purpose of this study was to determine if the rectus abdominis muscle in the dog model could be used as a transposition flap based on its proximal blood supply following ligation of the internal mammary artery. In 11 dogs, the left internal mammary artery and vein were ligated at the fifth intercostal space. Both the left and right rectus abdominis muscles were elevated from their respective beds, dividing the inferior epigastric and intercostal vascular pedicles.

Rhabdomyolysis and lower extremity compartment syndrome due to influenza B virus.

Rhabdomyolysis is an unusual complication following infection with influenza B virus. We recently managed a young boy who presented with severe rhabdomyolysis and bilateral lower extremity compartment syndrome due to infection with influenza B virus.

Applications of the posterior thigh flap.

As our population ages and spinal cord injuries continue at their present rate due to motor vehicle accidents and handgun injuries, the development of pressure sores will most likely increase in frequency. The three major populations at risk to develop pressure sores include the elderly, long-term hospital patients, and neurologically impaired patients. the posterior thigh flap evolved during our experience with the lower extremity muscle flaps.

Squamous cell carcinoma following breast augmentation.

Controversy over the safety of breast implants has increased significantly over the past several years. Several companies have discontinued their manufacture of silicone implants. Although there have been reports of breast cancer developing in a patient who previously had undergone breast augmentation, a review of the literature has failed to reveal a patient with cancer arising from the breast implant capsule.

Tissue expanders in children.

Tissue expanders are particularly applicable in the pediatric population. They are extremely well tolerated by children and can withstand the everyday play and trauma unique to children. Over the past 2 years, we have used 26 tissue expanders in 17 pediatric patients.