Publications by authors named "Palanisamy Saranya"
Article Synopsis
- Vitamin B12 deficiency can be caused by rare gastric neuroendocrine tumors (GNETs), which are often associated with high levels of gastrin and chronic stomach inflammation.
- A 48-year-old vegetarian male from South India experienced symptoms like jaundice and fatigue and was found to have macrocytic anemia and significant vitamin B12 deficiency, alongside a GNET diagnosis from gastric nodules.
- He received treatment including vitamin B12 supplementation, tumor resection, and antiviral therapy for hepatitis B, leading to a successful recovery and improvements in his health.
Overlap syndromes involving systemic sclerosis (SSc), rheumatoid arthritis (RA), and systemic lupus erythematosus (SLE) are rare and present significant diagnostic and therapeutic challenges. This case report details a 54-year-old female who presented with a constellation of clinical and serological features suggestive of both SSc, RA, and SLE. The patient's clinical course, diagnostic findings, and response to treatment are discussed highlighting the need for a multidisciplinary approach in managing such complex cases.
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- Autoimmune NMDA receptor encephalitis is a severe neuropsychiatric condition primarily affecting young individuals.
- The case report details a patient's journey, showcasing challenges in diagnosis and treatment.
- Symptoms started with psychosis and memory issues, quickly escalating to seizures and autonomic instability, typical of this disorder's progression.
Article Synopsis
- Pseudomembranous colitis (PC) is an inflammation of the colon mainly caused by Clostridium difficile, often triggered by antibiotic use, as seen in a case involving a 48-year-old man with severe health issues who presented with acute weakness and later developed PC during hospitalization.* -
- The patient's condition deteriorated due to complications like ventilator-associated pneumonia from multi-drug resistant bacteria, but he successfully transitioned off mechanical ventilation before facing severe diarrhea and abdominal pain linked to PC, confirmed by stool tests and imaging.* -
- Despite an initial treatment plan including vancomycin and metronidazole, he experienced a relapse of PC, which was confirmed through colonoscopy; this case underscores the need
The SARS-Cov-2 virus, which is evolving continuously and causing adverse effects throughout the world, needs an effective drug molecule for its treatment. There are several receptors of SARS Cov-2 which are targeted for its inhibition by many lead molecules both in-vitro and in-vivo. Papain like Protease (PLpro) is one of the two SARS-Cov-2 proteases that can be used as a drug target for SARS Cov-2.
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