Publications by authors named "Pakhrur Razi"

Background: The collaboration between pharmacists and veterinarians plays a crucial role in ensuring optimal animal healthcare. Understanding the willingness of veterinarians to collaborate with pharmacists and analyzing the prescribing trends by veterinarians are essential factors in improving the quality of veterinary care. By analyzing these aspects, valuable insights can be gained to enhance interprofessional collaboration and optimize medication management in veterinary practice.

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Strongly anti-oxidant and medicinal, L (NS) is utilized in conventional medicine to address a range of illnesses, including gastrointestinal, inflammatory and rheumatic illnesses. This study was carried out to investigate the effects of microwave processing on the physico-chemical properties of Moroccan-grown Nigella sativa seeds and oils, as well as to investigate the antioxidant qualities of black cumin oils under conditions of accelerated oxidation. The study's specific goal was to ascertain the effects of varying microwave power levels (500 and 750 W) and roasting times (5, 10, and 15 min) on the black cumin oils' quality indices, fatty acid and sterol content, carotenoid and chlorophyll levels, mineral profile, tocopherol amount, and overall antioxidant activity.

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Article Synopsis
  • This study investigated the link between anxiolytic drugs and the occurrence of Torsade de Pointes (TdP), a type of heart arrhythmia, using data from the FDA's Adverse Event Reporting System (FAERS) over a 30-year period.
  • Researchers identified 260 cases of TdP linked to anxiolytics and employed various data-mining algorithms to analyze the risk associated with these drugs.
  • The findings revealed six new signals of TdP risk linked to specific drugs, notably showing bromazepam and midazolam as the highest risk, while urging the need for more rigorous clinical studies to ensure patient safety.
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Memory loss is becoming an increasingly significant health problem, largely due to Alzheimer's disease (AD), which disrupts the brain in several ways, including causing inflammation and weakening the body's defenses. This study explores the potential of medicinal plants as a source of novel therapeutic agents for AD. First, we tested various plant extracts against acetylcholinesterase (AChE) , following molecular docking simulations with key AD-related protein targets such as MAO-B, P-gp, GSK-3β, and CD14.

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The development of natural substances derived from nature poses a significant challenge as technologies for the extraction and characterization of active principles advance. Hispolon has received a lot of attention in recent years, ascribable to its wide range of biological activities. It is a phenolic molecule that was extracted from several mushroom species such as Phellinus igniarius, Phellinus linteus, Phellinus lonicerinus, Phellinus merrillii, and Inonotus hispidus.

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Colorectal cancer (CRC) is one of the most significant forms of human cancer. It is characterized by its heterogeneity because several molecular factors are involved in contiguity and can link it to others without having a linear correlation. Among the factors influencing tumor transformation in CRC, transforming growth factor-beta (TGF-β) plays a key promoter role.

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