Purpose: This study provides a detailed analysis of the bioinorganic chemical composition of lens substance in patients with senile cataract using classical and spatial statistics methods.
Material And Methods: The study included 30 isolated human lenses. The light scattering ability (LSA) of the lens substance was evaluated using an original method.
Objective: The aim: To investigate the effectiveness of comprehensive approach in correctional work with older preschool children with speech disorders.
Patients And Methods: Materials and methods: The research was conducted in 2018-2022. The research involved 250 children aged 5-7 years, who were divided into two groups.
Objective: The aim is to determine the neuropsychological peculiarities of cognitive and communicative activities in adults with the extrapyramidal system disorders.
Patients And Methods: Materials and methods: The research was conducted during 2018-2021, during which a retrospective analysis of medical treatment records of the patients with extrapyramidal disorders of various etiologies was performed. The research involved 137 adult patients with extrapyramidal disorders: 93 persons with Parkinson's disease, 36 people with manganese encephalopathy, 5 persons with progressive supranuclear palsy and 3 people with Wilson-Konovalov disease.
Purpose: To analyze the chemical composition of the sclera and trabecular meshwork in patients with primary open-angle glaucoma (POAG) and to assess the impact of corneal-compensated intraocular pressure (IOP) on the chemistry of the drainage area.
Material And Methods: Biopsy specimens of the trabecular meshwork (89 specimens) and sclera (41 specimens) obtained from patients with POAG on maximal medical therapy were analyzed to determine the content of certain chemical elements - carbon (C), nitrogen (N), oxygen (O), aluminum (Al), calcium (Ca), chlorine (Cl), potassium (K), magnesium (Mg), sodium (Na), phosphorus (P), silicon (Si) and sulfur (S). The elements were selected based on chemical structure target tissue and sensitivity of the method used for analysis.
Purpose: To study the distribution of chemical elements in the placenta of pregnant women at 24-35 and 39-40 weeks of gestation, and to assess the possibility of using data on the levels of principle chemicals for predicting clinical manifestation of retinopathy of prematurity (ROP).
Material And Methods: The study examined 375 placenta tissue fragments of pregnant women for levels of the following chemical elements: carbon (C), nitrogen (N), oxygen (O), calcium (Ca), chlorine (Cl), potassium (K), sodium (Na) and phosphorus (P). Subjects were divided into 3 groups: 1st group consisted of 41 pregnant females (205 fragments of placenta tissue) at weeks 24-35 of gestation, whose children would not develop ROP; 2nd group included 14 mothers (70 fragments of placenta tissue) at weeks 39-40 of gestation; 3rd group - 20 pregnant (100 fragments of placenta tissue) at weeks 24-35 of gestation, whose children would be diagnosed with ROP.
The age-related cataract development consequent upon a loss of the lens capsule barrier properties proved to be associated with accumulation of sodium, calcium, phosphorus and potassium. For the first time the use of spatial cluster and correlation analyses showed that the physical light scattering in the crystalline lens volume depends on changes in the lens matter elemental composition. The fields of elevated concentrations of sodium, calcium, phosphorus, potassium and chlorine conformed to the lens capsule geometry and their clustering was similar to that of opacity fields in the lens body.
View Article and Find Full Text PDFBioinorganic chemical composition of the lens of human and experimental animals (cows, dogs, rats, rabbits) have been analyzed in various studies. In most cases, the studies employed different methods to determine the gross (total) composition of chemical elements and their concentrations in the examined samples. Less frequently, they included an assessment of the distribution of chemical elements in the lens and correlation of their concentration with its morphological changes.
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