J Pharm Pharm Sci
February 2017
Purpose: The importance of HLA-B*15:02 genotyping to avoid carbamazepine induced SJS/TEN and molecular modeling to predict the role of HLA-B*15:0 and AEDs induced SJS/TEN are investigated.
Methods: DNA was extracted from eighty-six patients. The patients were genotyped by AS-PCR.