Endoscopic submucosal dissection for colorectal polyps: outcome determining factors.

Background: Endoscopic submucosal dissection (ESD) has gained increasing popularity in the management of complicated colorectal polyps. However, clinical outcomes for ESD have remained highly inconsistent worldwide. This study investigated and analysed factors that significantly affect ESD outcomes.

Review on colorectal endoscopic submucosal dissection focusing on the technical aspect.

Background: Endoscopic submucosal dissection (ESD) enables removal of broad-based colorectal polyps or lateral spreading tumors with a higher rate of en bloc resection and a lower risk of local recurrence. However, it is technically demanding. Over the past 20 years, various equipment and innovative techniques have been developed to reduce the difficulty of ESD.

Case-Matched Analysis Comparing Endoscopic Submucosal Dissection and Surgical Removal of Difficult Colorectal Polyps.

Introduction: It is not uncommon to encounter colorectal polyps which could not be removed easily by simple polypectomy. Endoscopic submucosal dissection (ESD) has been a well-established method for doing so. We compared the result between ESD and surgical removal of these difficult colorectal polyps.

Prognostic significance of Cytokeratin 20-positive lymph node vascular endothelial growth factor A mRNA and chromodomain helicase DNA binding protein 4 in pN0 colorectal cancer patients.

Background: Cytokeratin 20-positive cells in lymph nodes from pN0 colorectal cancer (CRC) patients were detected previously by us. The aims of this study were to investigate which tumor metastasis-related genes were involved and their potential clinical significance.

Results: Fourteen of 84 (17%) genes were differentially expressed by at least 2-fold.