Measurement uncertainty for serum free light chain assays: estimation and implication on result interpretation.

Objectives: To estimate the measurement uncertainty (MU) and reference change value (RCV) for serum free light chain assays (sFLC), and to review their implications on result interpretation.

Design And Methods: Data from 6 to 9months of internal QC and up to 3.5years of EQA results were collected retrospectively, on the Roche Modular P analyzer and Dade Behring BN II nephelometer from two independent laboratories.

Validating urinary measurement of beta-2-microglobulin with a Roche reagent kit designed for serum measurements.

Objective: To validate the use of a Roche serum beta-2-microglobulin (B2MG) kit for urinary B2MG measurements, and to establish reference limits for urinary B2MG/creatinine ratio from healthy individuals.

Design And Methods: The Roche B2MG Tina-Quant serum kit was used to measure urinary B2MG immunoturbidimetrically.

Results: Using human urine as a diluent, the B2MG method was linear from 73-2156 μg/L.

Evaluation of a point-of-care glucose meter for general use in complex tertiary care facilities.

Objective: To evaluate the performance of the StatStrip glucose meter from Nova Biomedical for use in complex tertiary care facilities.

Methods: Performance evaluation was conducted in 6 clinical locations involving nurse end-users. Imprecision (CV)<5% was considered acceptable.