Publications by authors named "Paiva G"

Objective: To evaluate the risk factors for healthcare-related infections during the COVID-19 pandemic in intensive care units, to investigate the impact of COVID-19 on Central Line-Associated Bloodstream Infection, Catheter-Associated Urinary Tract Infection, and ventilator-associated pneumonia, and to describe healthcare-associated infections in the waves of the COVID-19 pandemic.

Methods: This nested case-control study was conducted in a 137-bed adult medical/surgical intensive care unit at a private hospital in São Paulo, Brazil, between January 11, 2019, and May 21, 2022. Case patients were identified using the Nosocomial Infection Control Committee database and control patients were identified using the intensive care unit's EPIMED system.

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Background/objectives: Obesity is influenced by biological, hormonal, and social factors, contributing to chronic diseases and burdening the healthcare system. Chronic stress and emotional eating are linked to weight gain, affecting eating behaviors and metabolism. This study aimed to assess the association between stress, eating behavior, and adiposity in obese women.

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High-risk gestational trophoblastic neoplasia encompasses patients with high volumes of disease or diffuse metastatic involvement who are unlikely to achieve remission with single-agent chemotherapy. Etoposide-based multi-drug regimens form the core of high-risk therapy. Second-line therapy includes platinum-based regimens.

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Article Synopsis
  • Complete and partial molar pregnancies result from abnormal fertilization and excessive growth of specific cells called syncytiotrophoblasts.
  • Early diagnosis has improved, reducing severe complications, but the risk of developing gestational trophoblastic neoplasia (GTN) remains the same.
  • Initial assessments should include blood tests and ultrasounds, and after treatment, ongoing monitoring is crucial; psychological support is recommended for all patients.
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Background: Attention-Deficit/Hyperactivity Disorder (ADHD) affects 5% of children and 2.5% of adults worldwide. Comorbidities are frequent, and Oppositional Defiant Disorder (ODD) reaches 50%.

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Currently, there is no intervention model for autism spectrum disorder (ASD) that addresses all levels and factors of the International Classification of Functioning, Disability and Health (ICF, WHO). The most researched programs focus on naturalistic, developmental and behavioral approaches to socio-communication. Less attention has been paid to motor and environmental reactivity aspects (behavior/interest restriction and sensory reactivity).

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  • The study examines the accessibility and pricing of fruits and vegetables in areas with and without Food and Nutrition Public Establishments in Belo Horizonte, Brazil, highlighting the importance of public policies in improving food security.
  • A cross-sectional audit of 148 food retailers showed that areas with these public establishments had greater availability of vegetables in fresh food retailers, while mixed food retailers demonstrated low availability in both areas.
  • Pricing analysis revealed that fresh food retailers generally offered lower prices compared to mixed food retailers, with significant differences observed between the two types in different areas.
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Purpose: To investigate whether there are differences in cepstral and spectral acoustic measures between women with behavioral dysphonia with and without laryngeal lesions and verify whether there is a correlation between such measures and the auditory-perceptual evaluation of voice quality.

Methods: The sample comprised 78 women with behavioral dysphonia without laryngeal lesions (BDWOL) and 68 with behavioral dysphonia with laryngeal lesions (vocal nodules) (BDWL). Cepstral peak prominence (CPP), cepstral peak prominence-smoothed (CPPS), spectral decrease, and H1-H2 (difference between the amplitude of the first and second harmonics) were extracted.

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Article Synopsis
  • Toehold switches are biosensors designed to detect specific RNAs, including those from viruses, with a programmable design process that allows for efficient engineering.* -
  • They often face issues with leaky translation in their OFF state, which reduces their sensitivity and effectiveness as biosensors.* -
  • A newly constructed serine integrase circuit significantly improves performance by minimizing leakage, increasing expression fold change, and lowering detection limits, making it easier to use in various biosensor applications.*
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Based on the genetic, morphological, and morphometric data of blood gamonts, we identified Hepatozoon parasites in colubrid snakes sampled in the Eastern Amazon region. Hepatozoon trigeminum was detected in the mussurana snake Clelia clelia and exhibited wide and elongated gamonts (mean dimensions: 14.25±0.

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Bacterial nanocellulose (BNC) has attained elevated interest due to its versatile structure and high resistance characteristics. Accordingly, efforts have been made in order to reduce its production costs, such as the employment of its by-products as a nutrient broth to yield the microorganism. Residual brewer's yeast is an excellent recourse, due to its high nutritional value and availability.

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Context: Artificial teeth are widely used in oral rehabilitation. Despite the benefits, they are more susceptible to colour changes, causing aesthetic problems.

Aims: To evaluate the effect of conventional cigarette and straw smoke on the colour of artificial teeth and the effectiveness of hygiene protocols in removing pigmentation.

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Purpose: This systematic review aimed to determine whether the pentoxifylline and tocopherol (PENTO) protocol effectively reduce the risk of osteoradionecrosis (ORN) in patients undergoing tooth extraction after head and neck radiotherapy.

Methods: We searched PubMed, SCOPUS, LILACS, EMBASE, Web of Science, and Cochrane databases up to August 2022. We considered only studies that included patients diagnosed with head and neck cancer undergoing tooth extraction with PENTO prophylaxis after radiotherapy.

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Caiman meat is considered exotic and its consumption has significantly increased due to its nutritional quality. This study aimed to evaluate the kinetics of water content (WC) and salt content (SC) at different temperatures (1, 5, 10 and 15 °C) and to evaluate the use of mathematical models to predict the mass transfer kinetics until equilibrium conditions during the wet salting of caiman tail fillets. Moisture and chloride analyses were performed throughout the wet salting process.

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Objective: To investigate the efficacy and toxicity of etoposide, methotrexate, actinomycin D alternating with cyclophosphamide, and vincristine (EMACO) for treatment of gestational trophoblastic neoplasia, and for factors independently associated with EMACO resistance and disease-specific death in an international cohort.

Methods: Medical records of GTN patients who received EMACO during 1986-2019 from gestational trophoblastic disease centers from four countries including the USA, Thailand, Hungary, and Brazil, were retrospectively reviewed. Among 335 GTN patients, 266 patients who received EMACO as primary chemotherapy were included in the primary treatment group, and 69 patients who received EMACO after relapse/resistance to single-agent chemotherapy were included in the prior treatment group.

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Synovial chondromatosis of the temporomandibular joint (TMJ) is a rare disease characterized by cartilaginous metaplasia of the mesenchymal remnants of the synovial membrane with formation of loose cartilaginous nodules. It is prevalent in middle-aged women and the main clinical characteristics are swelling, pain, and limited jaw movements. Diagnosis is difficult, especially in the early stages, because the signs and symptoms are like other TMJ diseases such as internal derangements and tumors.

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Article Synopsis
  • Gestational trophoblastic neoplasia (GTN) is a rare tumor from trophoblastic tissue, commonly arising after events like miscarriage or hydatidiform mole, and has high remission rates with chemotherapy.
  • Studies from various databases have reviewed GTN treatment, emphasizing the importance of timely diagnosis and treatment strategies.
  • Treatment options include multiagent chemotherapy for early and advanced cases, while surgery is reserved for specific situations, and resistance can be treated with either salvage chemotherapy or immunotherapy.
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  • The study aimed to evaluate the impact of the COVID-19 pandemic on the incidence and severity of molar pregnancy (MP) and postmolar gestational trophoblastic neoplasia (GTN) in Brazil.
  • Researchers collected data from 2,662 patients treated between 2015 and 2020, using a mix of retrospective cohort analysis and questionnaires to assess health conditions during the pandemic.
  • Results showed that while the overall incidence of MP/GTN remained stable during 2020, patients diagnosed during the pandemic had a higher likelihood of being diagnosed later in pregnancy and experienced longer delays in starting chemotherapy compared to the pre-pandemic years.
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L-Asparaginase (L-ASNase) is an enzyme applied in the treatment of lymphoid malignancies. However, an innovative L-ASNase with high yield and lower side effects than the commercially available preparations are still a market requirement. Here, a new-engineered Bacillus subtilis strain was evaluated for Aliivibrio fischeri L-ASNase II production, being the bioprocess development and the enzyme characterization studied.

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Math anxiety (MA) seems to result from an interaction of genetic vulnerability with negative experiences learning mathematics. Although mathematics achievement does not substantially differ between the sexes, MA levels are usually higher in girls. Molecular genetic markers of MA vulnerability have been seldom explored.

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Unlabelled: Monoamine oxidase A () polymorphisms have been associated with antisocial disorders. Less attention has been paid to the cognitive functioning of individuals with different alleles. No study has described the cognitive phenotype associated with the less frequent, low enzyme activity allele, MAOA_LPR*2R.

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Unlabelled: Expansive mutations in familial mental retardation 1 () gene have been associated with different phenotypes. Full mutations are associated with intellectual disability and autism spectrum disorder; premutations are associated with math learning difficulties and working memory impairments. In gray zone, neuropsychological development has not yet been described.

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For the rapidly growing aging demographic worldwide, robotic training methods could be impactful towards improving balance critical for everyday life. Here, we investigated the hypothesis that non-bodyweight supportive (nBWS) overground robotic balance training would lead to improvements in balance performance and balance confidence in older adults. Sixteen healthy older participants (69.

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Ethnopharmacological Relevance: The species Lippia origanoides Kunth, popularly known as "salva-de-marajó", is used in Brazilian traditional "quilombola" communities to treat menstrual cramps and uterine inflammation.

Aim Of The Study: Evaluate the spasmolytic activity of Lippia origanoides essential oil (LOO) on experimental models of uterine conditions related to menstrual cramps and investigate its mechanism of action.

Materials And Methods: Virgin rat-isolated uterus was mounted in the organ bath apparatus to evaluate the spasmolytic effect of LOO on basal tonus and contractions induced by carbachol, KCl, or oxytocin.

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Increasing balance confidence in older individuals is important towards improving their quality of life and reducing activity avoidance. Here, we investigated if balance confidence (perceived ability) and balance performance (ability) in older adults were related to one another and would improve after balance training. The relationship of balance confidence in conjunction with balance performance for varied conditions (such as limiting vision, modifying somatosensory cues, and also base of support) was explored.

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