Systemic anti-VEGF biosimilar therapy associated with improved macular anatomy and duration of effect in a patient with nearly recalcitrant neovascular age-related macular degeneration.

Purpose: To present a patient with neovascular AMD treated systemically with the biosimilar bevacizumab-awwb (Mvasi) with superior SRF resolution when compared to continuous and repeated intravitreal treatments.

Methods: Retrospective single case report.

Results: After 3 years of monthly aflibercept treatment for nAMD, the patient had persistent subretinal fluid (SRF).

Peripheral Exudative Hemorrhagic Chorioretinopathy (PEHCR): Diagnostic and Therapeutic Challenges.

Peripheral exudative hemorrhagic chorioretinopathy (PEHCR) is a peripheral retinal vascular abnormality that is likely underreported. We review the differential diagnoses, etiology, and treatment options for PEHCR. We present a case of an asymptomatic 72-year-old female referred following left eye fundus photography finding of the peripheral lesion.

NONSURGICAL RESOLUTION OF FULL-THICKNESS MACULAR HOLES WITHOUT VITREOMACULAR TRACTION.

Background/purpose: The purpose of this study was to report a case series of full-thickness macular holes without vitreomacular traction that resolved without surgery.

Methods: This study is a retrospective case series of 11 patients who demonstrated closure of full-thickness macular holes without surgical intervention.

Results: All full-thickness macular holes closed, with all patients having improvement in visual acuity.

Uveitis reactivation following recombinant zoster vaccination.

Purpose: Describe three cases of uveitis reactivation following immunization with recombinant zoster vaccine (RZV).

Observations: One patient developed reactivation of previously controlled multifocal choroiditis within one week of receiving RZV, requiring treatment with systemic corticosteroids. Two patients with previously controlled anterior uveitis developed new anterior segment inflammation after RZV; both were treated with topical corticosteroids and systemic antiviral therapy.