Updated review on novel therapies and ongoing clinical trials for high-risk non-muscle invasive bladder cancer.

Purpose Of Review: The treatment options for high-risk non-muscle invasive bladder cancer (NMIBC), particularly in the setting of BCG-unresponsive disease, remain limited. We provide updates on recent, promising trials for high-risk NMIBC and newly FDA approved therapies.

Recent Findings: Several therapies with diverse mechanisms of action have shown favorable results in both BCG-naïve and BCG-unresponsive settings for NMIBC.

Randomized Controlled Trial of Single-dose Perioperative Pregabalin in Ureteroscopy.

Purpose: Ureteroscopy is a commonly performed procedure, with postoperative pain that can lead to revisits and opioid prescribing. Perioperative gabapentinoids have shown promise in decreasing pain and opioid use. We hypothesized that single-dose perioperative pregabalin would be safe and efficacious for decreasing pain after ureteroscopy.

Coil embolization of a complex renal artery aneurysm using a new scaffold (Comaneci) device - A case report.

Advances in endovascular approaches have resulted in increasing utilization of minimally invasive techniques to treat visceral artery aneurysms including renal artery aneurysms (RAAs), with high rates of success. The basic endovascular approach to treating RAAs includes stent graft exclusion or coil embolization. Treatment of RAAs with wide necks or at the bifurcation of the main vessel is facilitated by scaffolding techniques, which have been previously described.

Percutaneous Lymphatic Maceration and Glue Embolization for High-output Chylous Ascites after Robot-assisted Laparoscopic Nephrectomy and Lymphadenectomy.

To propose minimally invasive percutaneous techniques in the management of high output chylous ascites, a known potential complication of retroperitoneal surgery associated with significant morbidity and mortality. Management has traditionally been based on successful treatment reported in the literature. However, refractory or high-output leaks often prove difficult to treat and there is little evidence on superior management.

Robotic Excision of Recurrent Renal Cell Carcinoma Inferior Vena Cava Tumor Thrombus.

Renal cell carcinoma (RCC) recurrence can present in nearly any location. Rarely, recurrence is within the venous system. Previous reports of such recurrent tumor thrombectomy have all used an open approach.