Functional consequences of interactions between FAK and epithelial membrane protein 2 (EMP2).

Purpose: Collagen gel contraction by ARPE-19 is controlled by epithelial membrane protein 2 (EMP2) through focal adhesion kinase (FAK) activation. The purpose of this study was to test the role of EMP2 in the cellular context of FAK activation.

Methods: The ARPE-19 cell line was recombinantly modified to increase the expression of EMP2 and was used in this study.