Publications by authors named "Paeivikki Repo"

Background: The aim of this study was to estimate the nationwide incidence of talus fractures (per 100 000 person-years) and to determine the incidence of operative treatment in the Finnish population.

Methods: Based on Finnish Care Register for Health Care data, all patients 18 years and older admitted to hospital with talar fractures between 1997 and 2020 were included.

Results: During the 24-year study period, 5247 patients with primary or secondary diagnoses of talar fracture were identified.

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Context: Exogenous insulin is reported to have both vasodilatory and vasoconstrictive effects on the microvasculature. Little is known about the associations of long-term endogenous insulin exposure with microvasculature.

Objective: To test the hypothesis that long-term exposure to high insulin levels in childhood and adulthood is associated with adverse changes in retinal microvasculature in adulthood in a population without diabetes.

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Green, aerobic oxidation of secondary alcohols to ketones poses a significant synthetic challenge. To address this, we have developed a highly active (DPA)CuI/ABNO catalyst system capable of aerobically oxidizing a wide range of secondary alcohols, including benzylic and aliphatic derivatives, yielding the corresponding ketones with high yields. The unique feature of this Cu(I) catalyst is its high stability, even in the presence of water.

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Natural disturbances may compromise the past and ongoing efforts to increase carbon sequestration and halt biodiversity loss in boreal forests. Measures to minimize the effects of forest disturbances i.e.

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Article Synopsis
  • The research presents a method that uses statistical analysis and robotics to optimize the conversion of glucose into two chemicals: methyl lactate and levulinic acid.
  • This automated synthesis process utilizes design of experiments techniques to efficiently model glucose transformation through the use of a specific catalyst and varying co-solvents.
  • In 58 experimental runs, the method successfully identified optimal conditions, achieving high yields of 75.9% for methyl lactate and 64.5% for levulinic acid through different reaction pathways.
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Article Synopsis
  • The BREAST-Q tool assesses health-related quality of life (HRQL) for new breast cancer patients, but lacks previous reference data for this group.
  • In a study of 627 newly diagnosed patients, 315 (50.2%) participated, where data on HRQL was collected and analyzed based on factors like age and body mass index (BMI).
  • Results showed lower scores in physical well-being compared to norms, and highlighted that increased BMI and younger age correlated with lower psychosocial, sexual well-being, and breast satisfaction.
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Uveal melanoma (UM) is a rare yet aggressive eye cancer causing over 50% mortality from metastasis. Familial UM, amounting to 1%-6% of patients in Finland and the United States, mostly lack identified genetic cause, while 8% show associations with other cancer syndromes. We searched novel genetic associations for predisposition to UM, additional to already studied BAP1 and MBD4, by using targeted amplicon sequencing of 19 genes associated with UM, BAP1, or renal cell carcinoma in 270 consecutively enrolled Finnish patients with UM.

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Article Synopsis
  • The study aimed to develop and validate Finnish versions of the BREAST-Q tool, which measures health-related quality of life for women receiving breast cancer treatments, including breast-conserving surgery, mastectomy, and reconstruction.
  • A total of 777 women were surveyed pre- and post-operation, with a notable participation rate of 665 (41%) in the study.
  • Results showed that the BREAST-Q modules had strong reliability and a high level of consistency, indicating they are effective for assessing the quality of life for Finnish women undergoing breast cancer treatment.
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Ageing-in-place policies encourage older adults to live at home as long as possible; however, this challenges the abilities of both formal care and informal help. Utilizing the results of my research, I introduce the term spatial solidarity to describe the help that older individuals give each other in age-related housing. One starting point for solidarity is the ability to relate to others.

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Steel slag, abundantly available at a low cost and containing over 30 wt% silica, is an attractive precursor for producing high-surface-area mesoporous silica. By employing a two-stage dissolution-precipitation method using 1 M HCl and 1 M NaOH, we extracted pure SiO, CaO, MgO, . from blast furnace slag (BFS).

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Background: The BODY-Q is a widely used patient-reported outcome measure for comprehensive assessment of treatment outcomes specific to patients undergoing body contouring surgery (BCS). However, for the BODY-Q to be meaningfully interpreted and used in clinical practice, minimal important difference (MID) scores are needed. A MID is defined as the smallest change in outcome measure score that patients perceive as important.

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Background And Aims: Retinal microvasculature characteristics predict cardiovascular morbidity and mortality. This study investigated associations of lifelong cardiovascular risk factors and effects of dietary intervention on retinal microvasculature in young adulthood.

Methods: The cohort is derived from the longitudinal Special Turku Coronary Risk Factor Intervention Project study.

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Arsenic is a hazardous element found in water sources, and removing it is crucial for ensuring a safe environment and water quality. Iron-based metal oxides efficiently remove arsenic; however, their small particle sizes make separation from water difficult after arsenic removal. Furthermore, the growing global issue of polymer waste further complicates environmental concerns.

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-Substituted pyridinium cations with the weakly coordinating anion [B(CF)] have been studied and crucial structural features in the sp C-H borylation catalysis of 3-methylthiophene have been identified. The electron-deficiency of the aromatic core of the cation is essential for activity together with accessible protons. The spectroscopic yield of the borylation of 3-methylthiophene with catecholborane (CatBH) was optimized up to 86% and the method was further applied to other substrates such as -alkylbenzenes.

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Coinage metals Cu, Ag, and Au are essential for modern electronics and their recycling from waste materials is becoming increasingly important to guarantee the security of their supply. Designing new sustainable and selective procedures that would substitute currently used processes is crucial. Here, we describe an unprecedented approach for the sequential dissolution of single metals from Cu, Ag, and Au mixtures using biomass-derived ionic solvents and green oxidants.

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Background: An effective patient-reported outcome measure for scars is needed to assess scar treatments and thus improve scar management. The recently developed SCAR-Q questionnaire for all scar types, which consists of the Appearance, Symptom, and Psychosocial impact scales, has been developed with patients' input. The aim of this study was to translate the SCAR-Q into Finnish and to assess its psychometric properties in burn patients.

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Background/aim: There are no studies assessing the long-term quality of life (QoL) following three-dimensional laparoscopy cholecystectomy (3D-LC) in patients with cholelithiasis (Chole).

Patients And Methods: A cohort of 200 patients with Chole were randomized into 3D-LC or minilaparotomy cholecystectomy (MC) groups. RAND-36 survey was performed before randomization, four weeks and five years postoperatively.

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Background And Purpose: Investigation of treatment options in the pediatric population necessitates the use of valid patient-reported outcome measures (PROMs). We aimed to assess the construct validity and internal consistency of the Quick Disabilities of the Arm, Shoulder and Hand (QuickDASH) in the pediatric population with upper extremity fractures treated both operatively and conservatively.

Patients And Methods: QuickDASH, along with several reference PROMs and objective outcome measures, was obtained from 148 5- to 18-year-old patients with a humeral medial epicondyle fracture or a fracture of the distal forearm in a cross-sectional setting with a single follow-up visit.

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Background: EOSQ-24 is a disease specific patient-reported outcome score used to assess the quality of life in patients with early-onset scoliosis. The aim of this study was to translate and cross-culturally adapt the English version of the EOSQ-24 to Finnish language and to assess the reliability and validity of the translation.

Methods: Cross-cultural adaptation and cross-cultural validation were performed to the Finnish translation of the EOSQ-24.

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Ultra-low-dose computed tomography (ULD-CT) may combine the high sensitivity of conventional computed tomography (CT) in detecting sarcoma pulmonary metastasis, with a radiation dose in the same magnitude as chest X-ray (CXR). Fifty patients with non-metastatic high-grade soft tissue sarcoma treated with curative intention were recruited. Their follow-up involved both CXR and ULD-CT to evaluate their different sensitivity.

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Industrial and mining wastewater, along with copper tailings, are typically highly acidic and contain copper and other heavy metals, which may contaminate and damage the environment. Copper (Cu) is, however, a valuable metal, making its removal and recovery from such wastewater and tailings environmentally and economically advantageous. Chelating ion exchange resins featuring bis-picolylamine functional groups are especially suitable for application requiring selective recovery of Cu(II) from highly acidic media.

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Porous organic polymers (POPs) and covalent organic frameworks (COFs) are hierarchical nano materials with variable applications. To our knowledge, this is the first report of a post-modified, non-renewable, DMSO-soluble M-POP/1,8-diazabicyclo[5.4.

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Objective: To examine health-related quality of life (HRQL) and satisfaction with appearance in patients who have undergone bariatric surgery (BS) with or without subsequent body contouring surgery (BCS) in relation to the general population normative for the BODY-Q.

Background: The long-term impact of BS with or without BCS has not been established using rigorously developed and validated patient-reported outcome measures. The BODY-Q is a patient-reported outcome measure developed to measure changes in HRQL and satisfaction with appearance in patients with BS and BCS.

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The exponential growth in textile fiber production and commensurate release of textile waste-based effluents into the environment has significant impacts on human wellbeing and the long-term planetary health. To abate these negative impacts and promote resource circularity, efforts are being made to recycle these waste materials via conversion into adsorbents for water decontamination. This review critically examines plant- and regenerated cellulose-based fibers for removing water pollutants such as heavy metals, dyes, pharmaceutical and petrochemical wastes.

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